EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
6.1.1.15 | Methanocaldococcus jannaschii | Q58635 | - |
- |
6.1.1.15 | Methanocaldococcus jannaschii DSM 2661 | Q58635 | - |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
6.1.1.15 | ATP + L-cysteine + tRNA | in later work it is shown that cysteine is attached to tRNA(Pro) and thus constitutes a misaminoacylation event and not a dual specificity. Addition of tRNA has a small threefold stimulatory effect on cysteine activation. The lack of a major role of tRNA in activation of cysteine suggests that the dual specificity enzyme must distinguish cysteine from proline directly, without the assistance of each cognate tRNA, to achieve the necessary specificity required for protein synthesis | Methanocaldococcus jannaschii | AMP + diphosphate + L-cysteinyl-tRNA | - |
? | |
6.1.1.15 | ATP + L-cysteine + tRNA | in later work it is shown that cysteine is attached to tRNA(Pro) and thus constitutes a misaminoacylation event and not a dual specificity. Addition of tRNA has a small threefold stimulatory effect on cysteine activation. The lack of a major role of tRNA in activation of cysteine suggests that the dual specificity enzyme must distinguish cysteine from proline directly, without the assistance of each cognate tRNA, to achieve the necessary specificity required for protein synthesis | Methanocaldococcus jannaschii DSM 2661 | AMP + diphosphate + L-cysteinyl-tRNA | - |
? | |
6.1.1.15 | ATP + L-proline + tRNAPro | activation of proline does not require tRNA. The dual specificity enzyme must distinguish cysteine from proline directly, without the assistance of each cognate tRNA, to achieve the necessary specificity required for protein synthesis | Methanocaldococcus jannaschii | AMP + diphosphate + L-prolyl-tRNAPro | - |
? | |
6.1.1.15 | ATP + L-proline + tRNAPro | activation of proline does not require tRNA. The dual specificity enzyme must distinguish cysteine from proline directly, without the assistance of each cognate tRNA, to achieve the necessary specificity required for protein synthesis | Methanocaldococcus jannaschii DSM 2661 | AMP + diphosphate + L-prolyl-tRNAPro | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
6.1.1.15 | Prolyl-tRNA synthetase | - |
Methanocaldococcus jannaschii |
6.1.1.15 | ProRS | - |
Methanocaldococcus jannaschii |