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Literature summary extracted from

  • Zhu, D.; Wang, Y.; Zhang, M.; Ikeda, H.; Deng, Z.; Cane, D.E.
    Product-mediated regulation of pentalenolactone biosynthesis in Streptomyces species by the MarR/SlyA family activators PenR and PntR (2013), J. Bacteriol., 195, 1255-1266.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.19.8 pentalenolactone F + O2 + NADPH + H+ Streptomyces exfoliatus
-
 pentalenolactone + NADP+ + H2O
-
 ?
1.14.19.8 pentalenolactone F + O2 + NADPH + H+ Streptomyces arenae
-
 pentalenolactone + NADP+ + H2O
-
 ?
1.14.19.8 pentalenolactone F + O2 + NADPH + H+ Streptomyces exfoliatus UC5319
-
 pentalenolactone + NADP+ + H2O
-
 ?
1.14.19.8 pentalenolactone F + O2 + NADPH + H+ Streptomyces arenae TUE469
-
 pentalenolactone + NADP+ + H2O
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.19.8 Streptomyces arenae
-
-
-
1.14.19.8 Streptomyces arenae TUE469
-
-
-
1.14.19.8 Streptomyces exfoliatus
-
-
-
1.14.19.8 Streptomyces exfoliatus UC5319
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.19.8 pentalenolactone F + O2 + NADPH + H+
-
 Streptomyces exfoliatus pentalenolactone + NADP+ + H2O
-
 ?
1.14.19.8 pentalenolactone F + O2 + NADPH + H+
-
 Streptomyces arenae pentalenolactone + NADP+ + H2O
-
 ?
1.14.19.8 pentalenolactone F + O2 + NADPH + H+
-
 Streptomyces exfoliatus UC5319 pentalenolactone + NADP+ + H2O
-
 ?
1.14.19.8 pentalenolactone F + O2 + NADPH + H+
-
 Streptomyces arenae TUE469 pentalenolactone + NADP+ + H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.19.8 penM
-
 Streptomyces exfoliatus
1.14.19.8 pntM
-
 Streptomyces arenae

Expression

EC Number Organism Comment Expression
1.14.19.8 Streptomyces exfoliatus transcription is activated by the PenR protein up
1.14.19.8 Streptomyces arenae transcription is activated by the PntR protein up