Literature summary extracted from
Kana, B.D.; Weinstein, E.A.; Avarbock, D.; Dawes, S.S.; Rubin, H.; Mizrahi, V.
Characterization of the cydAB-encoded cytochrome bd oxidase from Mycobacterium smegmatis (2001), J. Bacteriol., 183, 7076-7086.
Organism
EC Number |
Organism |
UniProt |
Comment |
Textmining |
---|
7.1.1.7 |
Mycolicibacterium smegmatis |
Q9L8R6 |
subunit cydB |
- |
7.1.1.7 |
Mycolicibacterium smegmatis |
Q9L8R7 and Q9L8R6 |
Q9L8R7 i.e. subunit cydA, Q9L8R6 i.e. subunit cydB |
- |
Synonyms
EC Number |
Synonyms |
Comment |
Organism |
---|
7.1.1.7 |
CydA |
- |
Mycolicibacterium smegmatis |
7.1.1.7 |
CydB |
- |
Mycolicibacterium smegmatis |
Cofactor
EC Number |
Cofactor |
Comment |
Organism |
Structure |
---|
7.1.1.7 |
heme |
two- to threefold increase in cydAB gene expression upon reduction of the pO2 of the growth medium from 21 to 0.5% air saturation with concomitant increase in d-heme absorbance in spectra of membranes isolated from wild-type Mycobacterium smegmatis cultured at 1% air saturation |
Mycolicibacterium smegmatis |
|
Expression
EC Number |
Organism |
Comment |
Expression |
---|
7.1.1.7 |
Mycolicibacterium smegmatis |
two- to threefold increase in cydAB gene expression upon reduction of the pO2 of the growth medium from 21 to 0.5% air saturation |
up |
General Information
EC Number |
General Information |
Comment |
Organism |
---|
7.1.1.7 |
physiological function |
inactivation of cydA or cydB by gene disruption results in loss of d-heme absorbance at 631 nm. Inactivation of cydA has no effect on the ability of Mycobacterium smegmatis to exit from stationary phase at 37 or 42°C. No discernible growth defect of the mutant is observed under moderately aerobic conditions, while the mutant displays a significant growth disadvantage when cocultured with the wild type under extreme microaerophilia. The cydA mutant displays a competitive growth disadvantage in the presence of the terminal oxidase inhibitor, cyanide, when cocultured with wild type at 21% air saturation in an oxystat |
Mycolicibacterium smegmatis |
7.1.1.7 |
physiological function |
inactivation of cydA or cydB gene disruption results in loss of d-heme absorbance at 631 nm |
Mycolicibacterium smegmatis |