EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
2.7.1.40 | 3-phosphoglycerate | allosteric activator. Regulation of the enzyme by a carboxylate molecule rather than a sugar phosphate may reflect a step in the evolution of glycolysis that predates the dominance of sugars in metabolism | Pyrobaculum aerophilum |
EC Number | Cloned (Comment) | Organism |
---|---|---|
2.7.1.40 | - |
Pyrobaculum aerophilum |
EC Number | Crystallization (Comment) | Organism |
---|---|---|
2.7.1.40 | hanging-drop vapor diffusion method at 18°C, crystal structure is determined to 2.2 A resolution | Pyrobaculum aerophilum |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.2.7.6 | D-glyceraldehyde-3-phosphate + H2O + oxidized ferredoxin | Pyrobaculum aerophilum | - |
3-phospho-D-glycerate + H+ + reduced ferredoxin | - |
ir | |
2.7.1.40 | ATP + pyruvate | Pyrobaculum aerophilum | the enzyme catalyzes the final step of glycolysis | ADP + phosphoenolpyruvate | - |
? | |
2.7.1.40 | ATP + pyruvate | Pyrobaculum aerophilum DSM 7523 | the enzyme catalyzes the final step of glycolysis | ADP + phosphoenolpyruvate | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.2.7.6 | Pyrobaculum aerophilum | - |
- |
- |
2.7.1.40 | Pyrobaculum aerophilum | Q8ZYE0 | - |
- |
2.7.1.40 | Pyrobaculum aerophilum DSM 7523 | Q8ZYE0 | - |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.7.1.40 | - |
Pyrobaculum aerophilum |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.2.7.6 | D-glyceraldehyde-3-phosphate + H2O + oxidized ferredoxin | - |
Pyrobaculum aerophilum | 3-phospho-D-glycerate + H+ + reduced ferredoxin | - |
ir | |
2.7.1.40 | ATP + pyruvate | - |
Pyrobaculum aerophilum | ADP + phosphoenolpyruvate | - |
? | |
2.7.1.40 | ATP + pyruvate | the enzyme catalyzes the final step of glycolysis | Pyrobaculum aerophilum | ADP + phosphoenolpyruvate | - |
? | |
2.7.1.40 | ATP + pyruvate | - |
Pyrobaculum aerophilum DSM 7523 | ADP + phosphoenolpyruvate | - |
? | |
2.7.1.40 | ATP + pyruvate | the enzyme catalyzes the final step of glycolysis | Pyrobaculum aerophilum DSM 7523 | ADP + phosphoenolpyruvate | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.2.7.6 | GAPOR | - |
Pyrobaculum aerophilum |
1.2.7.6 | glyceraldehyde 3-phosphate ferredoxin oxidoreductase | - |
Pyrobaculum aerophilum |
2.7.1.40 | PAE0819 | locus name | Pyrobaculum aerophilum |
EC Number | General Information | Comment | Organism |
---|---|---|---|
2.7.1.40 | physiological function | the enzyme catalyzes the final step of glycolysis | Pyrobaculum aerophilum |