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Literature summary extracted from

  • Wang, S.P.; He, G.L.; Chen, R.R.; Li, F.; Li, G.Q.
    The involvement of cytochrome P450 monooxygenases in methanol elimination in Drosophila melanogaster larvae (2012), Arch. Insect Biochem. Physiol., 79, 264-275.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.14.14.1 methanol dietary methanol exposure dramatically increases enzyme activity Drosophila melanogaster

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.14.1 RH + [reduced NADPH-hemoprotein reductase] + O2 Drosophila melanogaster
-
 ROH + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.14.1 Drosophila melanogaster
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.14.1 larva
-
 Drosophila melanogaster
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.14.1 RH + [reduced NADPH-hemoprotein reductase] + O2
-
 Drosophila melanogaster ROH + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.14.1 Cyp
-
 Drosophila melanogaster
1.14.14.1 CYP28A5
-
 Drosophila melanogaster
1.14.14.1 CYP305A1
-
 Drosophila melanogaster
1.14.14.1 CYP4AA1
-
 Drosophila melanogaster
1.14.14.1 CYP4E2
-
 Drosophila melanogaster
1.14.14.1 CYP9F2
-
 Drosophila melanogaster
1.14.14.1 cytochrome P450 monooxygenase
-
 Drosophila melanogaster

Expression

EC Number Organism Comment Expression
1.14.14.1 Drosophila melanogaster dietary methanol exposure increases gene expression of the genes CYP305A1, CYP9F2, CYP28A5, CYP4AA1, and CYP4E2 up