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Literature summary extracted from

  • Garcia-Leiro, A.; Cerdan, M.E.; Gonzalez-Siso, M.I.
    A functional analysis of Kluyveromyces lactis glutathione reductase (2010), Yeast, 27, 431-441.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.8.1.7 mitochondrion
-
 Kluyveromyces lactis 5739
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.8.1.7 glutathione disulfide + NADPH + H+ Kluyveromyces lactis
-
 glutathione + NADP+
-
 ?
1.8.1.7 glutathione disulfide + NADPH + H+ Kluyveromyces lactis NRRL-Y1140
-
 glutathione + NADP+
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.8.1.7 Kluyveromyces lactis
-
 i.e. CBS2359
-
1.8.1.7 Kluyveromyces lactis NRRL-Y1140
-
 i.e. CBS2359
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.8.1.7 glutathione disulfide + NADPH + H+
-
 Kluyveromyces lactis glutathione + NADP+
-
 ?
1.8.1.7 glutathione disulfide + NADPH + H+
-
 Kluyveromyces lactis NRRL-Y1140 glutathione + NADP+
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.8.1.7 GLR
-
 Kluyveromyces lactis

Cofactor

EC Number Cofactor Comment Organism Structure
1.8.1.7 NADPH
-
 Kluyveromyces lactis

General Information

EC Number General Information Comment Organism
1.8.1.7 malfunction cells lacking the enzyme show decreased resistance to oxidative stress (H2O2) and 2fold higher levels of reactive oxygen species and catalase activity than the wild type strain Kluyveromyces lactis
1.8.1.7 metabolism the enzyme is involved in glucose metabolism Kluyveromyces lactis