Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Han, J.Y.; Kim, H.J.; Kwon, Y.S.; Choi, Y.E.
    The Cyt P450 enzyme CYP716A47 catalyzes the formation of protopanaxadiol from dammarenediol-II during ginsenoside biosynthesis in Panax ginseng (2011), Plant Cell Physiol., 52, 2062-2073.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.14.14.120 expressed in Saccharomyces cerevisiae strain WAT21 Panax ginseng

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.14.120 dammarenediol-II + [reduced NADPH-hemoprotein reductase] + O2 Panax ginseng
-
 protopanaxadiol + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.14.120 Panax ginseng
-
 cultivar C.A. Meyer
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.14.120 root
-
 Panax ginseng
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.14.120 dammarenediol-II + [reduced NADPH-hemoprotein reductase] + O2
-
 Panax ginseng protopanaxadiol + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.14.120 CYP716A47
-
 Panax ginseng
1.14.14.120 dammarenediol 12-hydroxylase
-
 Panax ginseng
1.14.14.120 protopanaxadiol synthase
-
 Panax ginseng

Expression

EC Number Organism Comment Expression
1.14.14.120 Panax ginseng the gene is transcriptionally activated not only by methyl jasmonate treatment but also in transgenic ginseng that overexpresses squalene synthase and overproduces ginsenosides up