EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.3.1.9 | panosialin A | acylbenzenediol sulfate metabolites from Streptomyces sp. AN1761, potently inhibits bacterial enoyl-ACP reductases of Staphylococcus aureus, Streptococcus pneumoniae, and Mycobacterium tuberculosis | Mycobacterium tuberculosis | |
1.3.1.9 | panosialin A | acylbenzenediol sulfate metabolites from Streptomyces sp. AN1761, potently inhibits bacterial enoyl-ACP reductases of Staphylococcus aureus, Streptococcus pneumoniae, and Mycobacterium tuberculosis | Streptococcus pneumoniae | |
1.3.1.9 | panosialin B | acylbenzenediol sulfate metabolites from Streptomyces sp. AN1761, potently inhibits bacterial enoyl-ACP reductases of Staphylococcus aureus, Streptococcus pneumoniae, and Mycobacterium tuberculosis | Mycobacterium tuberculosis | |
1.3.1.9 | panosialin B | acylbenzenediol sulfate metabolites from Streptomyces sp. AN1761, potently inhibits bacterial enoyl-ACP reductases of Staphylococcus aureus, Streptococcus pneumoniae, and Mycobacterium tuberculosis | Streptococcus pneumoniae | |
1.3.1.9 | panosialin wA | acylbenzenediol sulfate metabolites from Streptomyces sp. AN1761, potently inhibits bacterial enoyl-ACP reductases of Staphylococcus aureus, Streptococcus pneumoniae, and Mycobacterium tuberculosis | Mycobacterium tuberculosis | |
1.3.1.9 | panosialin wA | acylbenzenediol sulfate metabolites from Streptomyces sp. AN1761, potently inhibits bacterial enoyl-ACP reductases of Staphylococcus aureus, Streptococcus pneumoniae, and Mycobacterium tuberculosis | Streptococcus pneumoniae | |
1.3.1.9 | panosialin wB | acylbenzenediol sulfate metabolites from Streptomyces sp. AN1761, potently inhibits bacterial enoyl-ACP reductases of Staphylococcus aureus, Streptococcus pneumoniae, and Mycobacterium tuberculosis | Mycobacterium tuberculosis | |
1.3.1.9 | panosialin wB | acylbenzenediol sulfate metabolites from Streptomyces sp. AN1761, potently inhibits bacterial enoyl-ACP reductases of Staphylococcus aureus, Streptococcus pneumoniae, and Mycobacterium tuberculosis | Streptococcus pneumoniae | |
1.3.1.39 | panosialin A | acylbenzenediol sulfate metabolites from Streptomyces sp. AN1761, potently inhibits bacterial enoyl-ACP reductases of Staphylococcus aureus, Streptococcus pneumoniae, and Mycobacterium tuberculosis | Staphylococcus aureus | |
1.3.1.39 | panosialin B | acylbenzenediol sulfate metabolites from Streptomyces sp. AN1761, potently inhibits bacterial enoyl-ACP reductases of Staphylococcus aureus, Streptococcus pneumoniae, and Mycobacterium tuberculosis | Staphylococcus aureus | |
1.3.1.39 | panosialin wA | acylbenzenediol sulfate metabolites from Streptomyces sp. AN1761, potently inhibits bacterial enoyl-ACP reductases of Staphylococcus aureus, Streptococcus pneumoniae, and Mycobacterium tuberculosis | Staphylococcus aureus | |
1.3.1.39 | panosialin wB | acylbenzenediol sulfate metabolites from Streptomyces sp. AN1761, potently inhibits bacterial enoyl-ACP reductases of Staphylococcus aureus, Streptococcus pneumoniae, and Mycobacterium tuberculosis | Staphylococcus aureus | |
1.3.1.39 | triclosan | - |
Staphylococcus aureus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.3.1.9 | Mycobacterium tuberculosis | - |
- |
- |
1.3.1.9 | Streptococcus pneumoniae | - |
- |
- |
1.3.1.39 | Staphylococcus aureus | Q6GI75 | - |
- |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.3.1.9 | FabI | - |
Streptococcus pneumoniae |
1.3.1.9 | InhA | - |
Mycobacterium tuberculosis |
1.3.1.39 | FabI | - |
Staphylococcus aureus |
EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|---|
1.3.1.9 | 0.0039 | - |
pH 6.5, temperature not specified in the publication | Streptococcus pneumoniae | panosialin A | |
1.3.1.9 | 0.0052 | - |
pH 6.5, temperature not specified in the publication | Streptococcus pneumoniae | panosialin B | |
1.3.1.9 | 0.0052 | - |
pH 6.5, temperature not specified in the publication | Streptococcus pneumoniae | panosialin wA | |
1.3.1.9 | 0.0055 | - |
pH 6.5, temperature not specified in the publication | Streptococcus pneumoniae | panosialin wB | |
1.3.1.9 | 0.0085 | - |
pH 8.0, temperature not specified in the publication | Mycobacterium tuberculosis | panosialin B | |
1.3.1.9 | 0.0091 | - |
pH 8.0, temperature not specified in the publication | Mycobacterium tuberculosis | panosialin wB | |
1.3.1.9 | 0.0096 | - |
pH 8.0, temperature not specified in the publication | Mycobacterium tuberculosis | panosialin wA | |
1.3.1.9 | 0.0118 | - |
pH 8.0, temperature not specified in the publication | Mycobacterium tuberculosis | panosialin A | |
1.3.1.39 | 0.00066 | - |
pH 6.5, temperature not specified in the publication | Staphylococcus aureus | triclosan | |
1.3.1.39 | 0.003 | - |
pH 6.5, temperature not specified in the publication | Staphylococcus aureus | panosialin wA | |
1.3.1.39 | 0.0043 | - |
pH 6.5, temperature not specified in the publication | Staphylococcus aureus | panosialin A | |
1.3.1.39 | 0.0046 | - |
pH 6.5, temperature not specified in the publication | Staphylococcus aureus | panosialin wB | |
1.3.1.39 | 0.0053 | - |
pH 6.5, temperature not specified in the publication | Staphylococcus aureus | panosialin B |