Any feedback?
Literature summary extracted from
- Synthesis of a bromotyrosine-derived natural product inhibitor of mycothiol-S-conjugate amidase (2004), Bioorg. Med. Chem. Lett., 14, 3785-3788.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.5.1.115 | bromotyrosine oxime | - |
Mycobacterium tuberculosis |  |
| 3.5.1.115 | hemibastidin-2 | - |
Mycobacterium tuberculosis | |
| 3.5.1.115 | psammaplin A | - |
Mycobacterium tuberculosis | |
| 3.5.1.115 | verongamine | - |
Mycobacterium tuberculosis | |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.5.1.115 | a mycothiol S-conjugate + H2O | Mycobacterium tuberculosis | - |
an N-acetyl L-cysteine-S-conjugate + 1-O-(2-amino-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.5.1.115 | Mycobacterium tuberculosis | - |
- |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.5.1.115 | a mycothiol S-conjugate + H2O | - |
Mycobacterium tuberculosis | an N-acetyl L-cysteine-S-conjugate + 1-O-(2-amino-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.5.1.115 | MCA | - |
Mycobacterium tuberculosis |
IC50 Value
| EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
|---|---|---|---|---|---|---|
| 3.5.1.115 | 0.03 | - |
pH and temperature not specified in the publication | Mycobacterium tuberculosis | bromotyrosine oxime | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
