Literature summary extracted from

McGrath, A.P.; Mithieux, S.M.; Collyer, C.A.; Bakhuis, J.G.; van den Berg, M.; Sein, A.; Heinz, A.; Schmelzer, C.; Weiss, A.S.; Guss, J.M.
Structure and activity of Aspergillus nidulans copper amine oxidase (2011), Biochemistry, 50, 5718-5730.

Crystallization (Commentary)

EC Number	Crystallization (Comment)	Organism
1.4.3.21	hanging drop vapor diffusion method, using 0.2M (NH4)2SO4 and 0.1 M sodium acetate (pH 4.4) with 25% (w/v) PEG 2000 MME	Aspergillus nidulans

Metals/Ions

EC Number	Metals/Ions	Comment	Organism	Structure
1.4.3.21	Cu2+	contains copper	Aspergillus nidulans

Molecular Weight [Da]

EC Number	Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
1.4.3.21	30000	-	x * 30000, SDS-PAGE	Aspergillus nidulans

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
1.4.3.21	alpha-casein + H2O + O2	Aspergillus nidulans	the enzyme oxidizes the lysine residues in alpha-casein protein	?	-	?
1.4.3.21	RCH2NH2 + H2O + O2	Aspergillus nidulans	-	RCHO + NH3 + H2O2	-	?
1.4.3.21	tropoelastin + H2O + O2	Aspergillus nidulans	the enzyme oxidizes the lysine residues in tropoelastin protein	?	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.4.3.21	Aspergillus nidulans	-	-	-

Purification (Commentary)

EC Number	Purification (Comment)	Organism
1.4.3.21	Q sepharose column chromatography	Aspergillus nidulans

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.4.3.21	alpha-casein + H2O + O2	the enzyme oxidizes the lysine residues in alpha-casein protein	Aspergillus nidulans	?	-	?
1.4.3.21	RCH2NH2 + H2O + O2	-	Aspergillus nidulans	RCHO + NH3 + H2O2	-	?
1.4.3.21	tropoelastin + H2O + O2	the enzyme oxidizes the lysine residues in tropoelastin protein	Aspergillus nidulans	?	-	?

Subunits

EC Number	Subunits	Comment	Organism
1.4.3.21	?	x * 30000, SDS-PAGE	Aspergillus nidulans

Synonyms

EC Number	Synonyms	Comment	Organism
1.4.3.21	Copper amine oxidase	-	Aspergillus nidulans
1.4.3.21	EC 1.4.3.6	formerly	Aspergillus nidulans
1.4.3.21	quinone- and copper-containing amine oxidase	-	Aspergillus nidulans

Cofactor

EC Number	Cofactor	Comment	Organism	Structure
1.4.3.21	2,4,5-trihydroxyphenylalanine quinone	-	Aspergillus nidulans

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Release 2023.1 (January 2023)