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Literature summary extracted from

  • Oxenrider, K.A.; Kennelly, P.J.
    A protein-serine phosphatase from the halophilic archaeon Haloferax volcanii (1993), Biochem. Biophys. Res. Commun., 194, 1330-1335.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.3.16 4-nitrophenyl phosphate 10 mM, 89% inhibition Haloferax volcanii
3.1.3.16 diethylpyrocarbonate
-
 Haloferax volcanii
3.1.3.16 diphosphate 10 mM, complete inhibition Haloferax volcanii
3.1.3.16 molybdate 1 mM, 70% inhibition Haloferax volcanii
3.1.3.16 additional information activity is unaffected by other potential inhibitors or activators such as polyamines, heparin, cyclic nucleotides, Ca2+/calmodulin, tartrate, tetramisole, okadaic acid, microcystin LR, or sulfhydryl-modifying agents Haloferax volcanii
3.1.3.16 NaF 50 mM, 47% inhibition Haloferax volcanii
3.1.3.16 phosphate 50 mM, complete inhibition Haloferax volcanii
3.1.3.16 vanadate 1 mM, complete inhibition Haloferax volcanii
3.1.3.16 Zn2+ 5 mM, complete inhibition Haloferax volcanii

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.1.3.16 Cd2+ 20 mM, stimulation is about 45% compared to that with Mn2+ Haloferax volcanii
3.1.3.16 Co2+ 20 mM, stimulation is about 15% compared to that with Mn2+ Haloferax volcanii
3.1.3.16 Mn2+ 20 mM, stimulates Haloferax volcanii
3.1.3.16 Ni2+ 20 mM, stimulation is about 5% compared to that with Mn2+ Haloferax volcanii

Organism

EC Number Organism UniProt Comment Textmining
3.1.3.16 Haloferax volcanii
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.3.16 [protein]-L-serine phosphate + H2O the enzyme dephosphorylates phosphoseryl residues in casein, mixed histones, and phosphorylase a, but not phosphotyrosyl residues in reduced, carboxyamidomethylated and maleylated lysozyme Haloferax volcanii [protein]-L-serine + phosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.1.3.16 protein-serine phosphatase
-
 Haloferax volcanii