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Literature summary extracted from

  • Montero-Barrientos, M.; Hermosa, R.; Cardoza, R.E.; Gutierrez, S.; Monte, E.
    Functional analysis of the Trichoderma harzianum nox1 gene, encoding an NADPH oxidase, relates production of reactive oxygen species to specific biocontrol activity against Pythium ultimum (2011), Appl. Environ. Microbiol., 77, 3009-3016.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.6.3.1 gene nox1, DNA and amino acid sequence determination and analysis, quantitative real-time PCR expression analysis, recombinant expression in wild-type Trichoderma harzianum leading to increased levels of Nox1, which is accompanied by an increase in reactive oxgen species production during their direct confrontation with Pythium ultimum. The transformants display an increased hydrolytic pattern Trichoderma harzianum

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.6.3.1 NADPH + H+ + O2 Trichoderma harzianum
-
 NADP+ + H2O2
-
 ?
1.6.3.1 NADPH + H+ + O2 Trichoderma harzianum T34
-
 NADP+ + H2O2
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.6.3.1 Trichoderma harzianum F4ZCJ9 gene nox1
-
1.6.3.1 Trichoderma harzianum T34 F4ZCJ9 gene nox1
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.6.3.1 mycelium
-
 Trichoderma harzianum
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.6.3.1 NADPH + H+ + O2
-
 Trichoderma harzianum NADP+ + H2O2
-
 ?
1.6.3.1 NADPH + H+ + O2
-
 Trichoderma harzianum T34 NADP+ + H2O2
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.6.3.1 NOX1
-
 Trichoderma harzianum

Cofactor

EC Number Cofactor Comment Organism Structure
1.6.3.1 FAD Nox1 protein reveals the presence of six transmembrane domains and one FAD/NADPH binding cytosolic domain Trichoderma harzianum
1.6.3.1 NADPH Nox1 protein reveals the presence of six transmembrane domains and one FAD/NADPH binding cytosolic domain Trichoderma harzianum

General Information

EC Number General Information Comment Organism
1.6.3.1 physiological function Nox1 relates production of reactive oxygen species to specific biocontrol activity against Pythium ultimum, but not Botrytis cinerea or Rhizoctonia solani Trichoderma harzianum