Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Paccalet, T.; Coulombe, Z.; Tremblay, J.P.
    Ganglioside GM3 levels are altered in a mouse model of HIBM: GM3 as a cellular marker of the disease (2010), PLoS ONE, 5, e10055.
    View publication on PubMedView publication on EuropePMC

Application

EC Number Application Comment Organism
2.4.3.9 medicine the enzyme is a marker of hereditary inclusion body myopathy Mus musculus

Organism

EC Number Organism UniProt Comment Textmining
2.4.3.9 Mus musculus O88829
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.3.9 muscle
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.3.9 CMP-N-acetylneuraminate + beta-D-galactosyl-1,4-beta-D-glucosylceramide
-
 Mus musculus CMP + N-acetylneuraminyl-2,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.4.3.9 beta-galactoside alpha-2,3-sialyltransferase 5
-
 Mus musculus
2.4.3.9 ST3Gal5
-
 Mus musculus

Expression

EC Number Organism Comment Expression
2.4.3.9 Mus musculus enzyme mRNA levels are significantly lower (64%) in mouse muscles of a model of hereditary inclusion body myopathy harboring the M712T mutation of UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase compared to control mice down