EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
2.7.1.21 | H121N | the mutant has less than 7% kinase activity compared to the wild type enzyme | Mus musculus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
2.7.1.21 | cytosol | thymidine kinase 1 | Mus musculus | 5829 | - |
2.7.1.21 | mitochondrion | thymidine kinase 2 | Mus musculus | 5739 | - |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
2.7.1.21 | 25000 | - |
2 * 25000, isoform TK1, SDS-PAGE | Mus musculus |
2.7.1.21 | 25500 | - |
2 * 25500, isoform TK1, calculated from amino acid sequence | Mus musculus |
2.7.1.21 | 60000 | - |
isoform TK1, gel filtration | Mus musculus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.1.21 | Mus musculus | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.1.21 | ATP + thymidine | - |
Mus musculus | ADP + dTMP | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
2.7.1.21 | homodimer | 2 * 25000, isoform TK1, SDS-PAGE | Mus musculus |
2.7.1.21 | homodimer | 2 * 25500, isoform TK1, calculated from amino acid sequence | Mus musculus |
2.7.1.21 | monomer or dimer | isoform TK2 | Mus musculus |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.7.1.21 | thymidine kinase 1 | - |
Mus musculus |
2.7.1.21 | thymidine kinase 2 | - |
Mus musculus |
2.7.1.21 | TK1 | - |
Mus musculus |
2.7.1.21 | TK2 | - |
Mus musculus |
EC Number | General Information | Comment | Organism |
---|---|---|---|
2.7.1.21 | malfunction | isoform TK2-deficient animal show growth retardation and premature death | Mus musculus |