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Literature summary extracted from

  • Dickens, M.L.; Strohl, W.R.
    Isolation and characterization of a gene from Streptomyces sp. strain C5 that confers the ability to convert daunomycin to doxorubicin on Streptomyces lividans TK24 (1996), J. Bacteriol., 178, 3389-3395.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.14.13.181 expression in Streptomyces lividans TK24 Streptomyces sp.

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.14.13.181 46096
-
 x * 46096, calculated from sequence Streptomyces sp.

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.13.181 additional information Streptomyces sp. the enzyme convert daunomycin to doxorubicin ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.13.181 Streptomyces sp. Q59971
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.13.181 additional information the enzyme convert daunomycin to doxorubicin Streptomyces sp. ?
-
 ?
1.14.13.181 additional information daunomycinone (daunomycin aglycone), carminomycin, 13-dihydrocarminomycin, idarubicin, and aklavin are not apparent substrates for DoxA Streptomyces sp. ?
-
 ?

Subunits

EC Number Subunits Comment Organism
1.14.13.181 ? x * 46096, calculated from sequence Streptomyces sp.

Synonyms

EC Number Synonyms Comment Organism
1.14.13.181 DoxA
-
 Streptomyces sp.