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Literature summary extracted from

  • Orywal, K.; Jelski, W.; Zdrodowski, M.; Szmitkowski, M.
    The activity of class I, II, III and IV alcohol dehydrogenase isoenzymes and aldehyde dehydrogenase in cervical cancer (2011), Clin. Biochem., 44, 1231-1234.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.1 1-butanol + NAD+ Homo sapiens
-
 butanal + NADH + H+
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.1 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.1 adenocarcinoma cell
-
 Homo sapiens
-
1.1.1.1 cervical cancer cell
-
 Homo sapiens
-
1.1.1.1 additional information activity of ADH isoenzymes and ALDH in cervical carcinoma and healthy tissues., overview Homo sapiens
-
1.1.1.1 uterus
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.1 1-butanol + NAD+
-
 Homo sapiens butanal + NADH + H+
-
 ?
1.1.1.1 3-nitrobenzaldehyde + NADH + H+ class IV isozyme, reductive activity Homo sapiens 3-nitrobenzyl alcohol + NAD+
-
 ?
1.1.1.1 4-methoxy-1-naphthaldehyde + NAD+ fluorogenic substrate of class I and II isozymes Homo sapiens 4-methoxy-1-naphthol + NADH + H+
-
 ?
1.1.1.1 4-nitrosodimethylaniline + NAD+ photometric assay substrate Homo sapiens ? + NADH + H+
-
 ?
1.1.1.1 6-methoxy-2-naphthaldehyde + NADH + H+ class II isozyme, reductive activity Homo sapiens (6-methoxynaphthalen-2-yl)methanol + NAD+
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.1.1.1 ADH
-
 Homo sapiens
1.1.1.1 aldehyde dehydrogenase
-
 Homo sapiens
1.1.1.1 ALDH
-
 Homo sapiens
1.1.1.1 class I ADH
-
 Homo sapiens
1.1.1.1 class II ADH
-
 Homo sapiens
1.1.1.1 class III ADH
-
 Homo sapiens
1.1.1.1 class IV ADH
-
 Homo sapiens

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
1.1.1.1 25
-
 assay at Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.1.1.1 7.5
-
 assay at, class IV enzyme, reduction reaction Homo sapiens
1.1.1.1 7.6
-
 assay at, class II enzyme, reduction reaction Homo sapiens
1.1.1.1 8
-
 assay at, class III enzyme, reduction reaction Homo sapiens
1.1.1.1 8.5
-
 assay at, total ADH activity Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.1 NAD+
-
 Homo sapiens