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Literature summary extracted from

  • Li, Z.H.; Cintron, R.; Koon, N.A.; Moreno, S.N.
    The N-terminus and the chain-length determination domain play a role in the length of the isoprenoid product of the bifunctional Toxoplasma gondii farnesyl diphosphate synthase (2012), Biochemistry, 51, 7533-7540.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.5.1.10 expressed in Escherichia coli BL21(DE3) cells Toxoplasma gondii

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.5.1.10 58000
-
 x * 58000, native enzyme, SDS-PAGE Toxoplasma gondii
2.5.1.10 69600
-
 x * 69600, calculated from amino acid sequence Toxoplasma gondii
2.5.1.10 75000
-
 x * 75000, recombinant enzyme, SDS-PAGE Toxoplasma gondii

Organism

EC Number Organism UniProt Comment Textmining
2.5.1.10 Toxoplasma gondii Q197X6
-
-
2.5.1.10 Toxoplasma gondii RH Q197X6
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.5.1.10 anti-FLAG M2 affinity resin chromatography and nickel affinity column chromatography Toxoplasma gondii

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.5.1.10 tachyzoite
-
 Toxoplasma gondii
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.5.1.10 geranyl diphosphate + isopentenyl diphosphate
-
 Toxoplasma gondii diphosphate + (2E,6E)-farnesyl diphosphate
-
 ?
2.5.1.10 geranyl diphosphate + isopentenyl diphosphate
-
 Toxoplasma gondii RH diphosphate + (2E,6E)-farnesyl diphosphate
-
 ?

Subunits

EC Number Subunits Comment Organism
2.5.1.10 ? x * 75000, recombinant enzyme, SDS-PAGE Toxoplasma gondii
2.5.1.10 ? x * 58000, native enzyme, SDS-PAGE Toxoplasma gondii
2.5.1.10 ? x * 69600, calculated from amino acid sequence Toxoplasma gondii

Synonyms

EC Number Synonyms Comment Organism
2.5.1.10 farnesyl diphosphate synthase Toxoplasma gondii possesses a bifunctional farnesyl diphosphate/geranylgeranyl diphosphate synthase Toxoplasma gondii
2.5.1.10 FPPS
-
 Toxoplasma gondii