EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.2.3 | Homo sapiens | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.2.3 | D-ATP + 1,3-bisphospho-D-glycerate | - |
Homo sapiens | ? | - |
? | |
2.7.2.3 | D-CDP + 1,3-bisphospho-D-glycerate | - |
Homo sapiens | ? | - |
? | |
2.7.2.3 | L-ATP + 1,3-bisphospho-D-glycerate | - |
Homo sapiens | ? | - |
? | |
2.7.2.3 | L-CDP + 1,3-bisphospho-D-glycerate | - |
Homo sapiens | ? | - |
? | |
2.7.2.3 | additional information | molecular dynamics simulations are carried out with four different nucleotides (D-/L-ADP and D-/L-CDP) in complex with hPGK and 1,3-bisphospho-D-glycerate (bPG). The binding affinities of CDPs (both enantiomers) for hPGK are found very weak while D- and L-ADP are better substrates. The binding affinity of the bPG substrate is found to be lower in presence of D-ADP than L-ADP which indicates a potential antagonistic effect on one substrate to the other | Homo sapiens | ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.7.2.3 | hPGK | - |
Homo sapiens |