Literature summary extracted from

Lashkov, A.A.; Sotnichenko, S.E.; Prokofiev, I.I.; Gabdulkhakov, A.G.; Agapov, I.I.; Shtil, A.A.; Betzel, C.; Mironov, A.S.; Mikhailov, A.M.
X-ray structure of Salmonella typhimurium uridine phosphorylase complexed with 5-fluorouracil and molecular modelling of the complex of 5-fluorouracil with uridine phosphorylase from Vibrio cholerae (2012), Acta Crystallogr. Sect. D, 68, 968-974.

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
2.4.2.3	-	Vibrio cholerae serotype O1
2.4.2.3	-	Salmonella enterica subsp. enterica serovar Typhimurium

Crystallization (Commentary)

EC Number	Crystallization (Comment)	Organism
2.4.2.3	in complex with 5-fluorouridine, to 2.2 A resolution. The quaternary structure is represented by a hexamer comprised of six identical subunits. The packing of subunits in the hexamer can be described by the symmetry point group L33L2. The main structural and functional unit in the ligand-free state is a homodimer.The hexameric structure is formed by three homodimers with hydrophobic and hydrogen-bond interactions	Salmonella enterica subsp. enterica serovar Typhimurium
2.4.2.3	in silico model of the complex with 5-fluorouracil. The quaternary structure is represented by a hexamer comprised of six identical subunits. The packing of subunits in the hexamer can be described by the symmetry point group L33L2. The hexameric structure of the complex is stabilized by hydrophobic interactions and hydrogen bonds between the amino-acid residues of adjacent homodimers	Vibrio cholerae serotype O1

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.4.2.3	Salmonella enterica subsp. enterica serovar Typhimurium	P0A1F6	-	-
2.4.2.3	Vibrio cholerae serotype O1	-	-	-

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Release 2023.1 (January 2023)