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Literature summary extracted from

  • Macbeth, M.R.; Schubert, H.L.; Vandemark, A.P.; Lingam, A.T.; Hill, C.P.; Bass B.L.
    Inositol hexakisphosphate is bound in the ADAR2 core and required for RNA editing (2005), Science, 309, 1534-1539.
    View publication on PubMedView publication on EuropePMC

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.5.4.37 Zinc the structure reveals zinc in the active site Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.5.4.37 Homo sapiens P78563
-
-

Synonyms

EC Number Synonyms Comment Organism
3.5.4.37 hADAR2-D
-
Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
3.5.4.37 Inositol hexakisphosphate is buried within the enzyme core, contributing to the protein fold. Inositol hexakisphosphate is required for activity. Amino acids that coordinate inositol hexakisphosphate in the crystal structure are conserved in some adenosine deaminases that act on tRNA Homo sapiens