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Literature summary extracted from
- Twelve Positions in a beta-lactamase that can expand its substrate spectrum with a single amino acid substitution (2012), PLoS ONE, 7, e37585.
Protein Variants
| EC Number | Protein Variants | Comment | Organism |
|---|---|---|---|
| 3.5.2.6 | additional information | analysis of 516 mutated enzymes that acquired the ceftazidime-hydrolyzing activity, and identification of twelve positions with single amino acid substitutions, co-localized at the active-site pocket area. single amino acid substitutions are found at positions C89, N136, L162, R164, E166, L169, N170, T171, A172, P174, D176, D179. All substitutions cause a congruent effect, expanding the space in a conserved structure called the omega loop, which in turn increased flexibility at the active site | Burkholderia thailandensis |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.5.2.6 | Burkholderia thailandensis | - |
- |
- |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.5.2.6 | PenA | - |
Burkholderia thailandensis |
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Release 2023.1 (January 2023)
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