BRENDA - Enzyme Database

Post-genome research on the biosynthesis of ergot alkaloids

Li, S.M.; Unsoeld, I.A.; Planta Med. 72, 1117-1120 (2006) View publication on PubMed

Data extracted from this reference:

Cloned(Commentary)
EC Number
Cloned (Commentary)
Organism
2.5.1.100
gene fgaPT1, DNA and amino acid sequence determination and analysis, genetic organization, phylogenetic analysis
Aspergillus fumigatus
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
2.5.1.100
fumigaclavine A + dimethylallyl diphosphate
Aspergillus fumigatus
-
fumigaclavine C + diphosphate
-
-
?
2.5.1.100
fumigaclavine A + dimethylallyl diphosphate
Aspergillus fumigatus Af293
-
fumigaclavine C + diphosphate
-
-
?
Organism
EC Number
Organism
UniProt
Commentary
Textmining
2.5.1.100
Aspergillus fumigatus
-
gene fgaPT1, in the gene cluster of fumigaclabvine C biosynthesis
-
2.5.1.100
Aspergillus fumigatus Af293
-
gene fgaPT1, in the gene cluster of fumigaclabvine C biosynthesis
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
Substrate Product ID
2.5.1.100
fumigaclavine A + dimethylallyl diphosphate
-
720777
Aspergillus fumigatus
fumigaclavine C + diphosphate
-
-
-
?
2.5.1.100
fumigaclavine A + dimethylallyl diphosphate
-
720777
Aspergillus fumigatus Af293
fumigaclavine C + diphosphate
-
-
-
?
Synonyms
EC Number
Synonyms
Commentary
Organism
2.5.1.100
FgaPT1
-
Aspergillus fumigatus
Cloned(Commentary) (protein specific)
EC Number
Commentary
Organism
2.5.1.100
gene fgaPT1, DNA and amino acid sequence determination and analysis, genetic organization, phylogenetic analysis
Aspergillus fumigatus
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
2.5.1.100
fumigaclavine A + dimethylallyl diphosphate
Aspergillus fumigatus
-
fumigaclavine C + diphosphate
-
-
?
2.5.1.100
fumigaclavine A + dimethylallyl diphosphate
Aspergillus fumigatus Af293
-
fumigaclavine C + diphosphate
-
-
?
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ID
2.5.1.100
fumigaclavine A + dimethylallyl diphosphate
-
720777
Aspergillus fumigatus
fumigaclavine C + diphosphate
-
-
-
?
2.5.1.100
fumigaclavine A + dimethylallyl diphosphate
-
720777
Aspergillus fumigatus Af293
fumigaclavine C + diphosphate
-
-
-
?
General Information
EC Number
General Information
Commentary
Organism
2.5.1.100
metabolism
FgaPT1 catalyzes the last step of fumigaclavine C biosynthesis, i.e. the prenylation of fumigaclavine A at C-2 position of the indole nucleus, which is included in the biosynthesis of ergot alkaloids
Aspergillus fumigatus
General Information (protein specific)
EC Number
General Information
Commentary
Organism
2.5.1.100
metabolism
FgaPT1 catalyzes the last step of fumigaclavine C biosynthesis, i.e. the prenylation of fumigaclavine A at C-2 position of the indole nucleus, which is included in the biosynthesis of ergot alkaloids
Aspergillus fumigatus