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Literature summary extracted from

  • Francis, J.S.; Strande, L.; Markov, V.; Leone, P.
    Aspartoacylase supports oxidative energy metabolism during myelination (2012), J. Cereb. Blood Flow Metab., 32, 1725-1736.
    View publication on PubMedView publication on EuropePMC

Organism

EC Number Organism UniProt Comment Textmining
3.5.1.15 Mus musculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.5.1.15 brain
-
 Mus musculus
-
3.5.1.15 oligodendrocyte
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.5.1.15 N-acetyl-L-aspartate + H2O
-
 Mus musculus L-aspartate + acetate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.5.1.15 ASPA
-
 Mus musculus

Expression

EC Number Organism Comment Expression
3.5.1.15 Mus musculus enzyme expression is decreased during the early stages of postnatal development down

General Information

EC Number General Information Comment Organism
3.5.1.15 physiological function aspartoacylase activity supports adenosine triphosphate synthesis in oligodendrocytes during hypoglycemia in vitro. The loss of enzyme function during the early stages of postnatal development significantly compromises oligodendrocyte oxidative integrity Mus musculus