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Literature summary extracted from

  • Jin, Y.; Xin, Y.; Zhang, W.; Ma, Y.
    Mycobacterium tuberculosis Rv1302 and Mycobacterium smegmatis MSMEG 4947 have WecA function and MSMEG 4947 is required for the growth of M. smegmatis (2010), FEMS Microbiol. Lett., 310, 54-61.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.8.35 expressed in wecA-defective Escherichia coli MV501 cells Mycolicibacterium smegmatis
2.7.8.35 expressed in wecA-defective Escherichia coli MV501 cells Mycobacterium tuberculosis

Organism

EC Number Organism UniProt Comment Textmining
2.7.8.35 Mycobacterium tuberculosis
-
-
-
2.7.8.35 Mycolicibacterium smegmatis
-
-
-
2.7.8.35 Mycolicibacterium smegmatis mc(2)155 / ATCC 700084
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.8.35 UDP-N-acetyl-alpha-D-glucosamine + trans,octacis-decaprenyl phosphate
-
 Mycolicibacterium smegmatis UMP + N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol
-
 r
2.7.8.35 UDP-N-acetyl-alpha-D-glucosamine + trans,octacis-decaprenyl phosphate
-
 Mycobacterium tuberculosis UMP + N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol
-
 r
2.7.8.35 UDP-N-acetyl-alpha-D-glucosamine + trans,octacis-decaprenyl phosphate
-
 Mycolicibacterium smegmatis mc(2)155 / ATCC 700084 UMP + N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol
-
 r

Synonyms

EC Number Synonyms Comment Organism
2.7.8.35 MSMEG 4947
-
 Mycolicibacterium smegmatis
2.7.8.35 Rv1302
-
 Mycobacterium tuberculosis
2.7.8.35 UDP-GlcNAc: undecaprenyl phosphate GlcNAc-1-phosphate transferase
-
 Mycolicibacterium smegmatis
2.7.8.35 UDP-GlcNAc: undecaprenyl phosphate GlcNAc-1-phosphate transferase
-
 Mycobacterium tuberculosis
2.7.8.35 WecA
-
 Mycolicibacterium smegmatis
2.7.8.35 WecA
-
 Mycobacterium tuberculosis

General Information

EC Number General Information Comment Organism
2.7.8.35 malfunction the disruption of MSMEG 4947 in the Mycobaterium smegmatis genome results in the loss of viability at 42°C and causes drastic morphological changes like pear shape and larger diameter Mycolicibacterium smegmatis
2.7.8.35 metabolism the enzyme catalyzes the first step in the biosynthesis of lipopolysaccharide O-antigen Mycolicibacterium smegmatis
2.7.8.35 metabolism the enzyme catalyzes the first step in the biosynthesis of lipopolysaccharide O-antigen Mycobacterium tuberculosis