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Literature summary extracted from

  • Steffan, N.; Grundmann, A.; Yin, W.B.; Kremer, A.; Li, S.M.
    Indole prenyltransferases from fungi: a new enzyme group with high potential for the production of prenylated indole derivatives (2009), Curr. Med. Chem., 16, 218-231.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.5.1.100 gene fgaaPT1, DNA and amino acid sequence determination and analysis, phylogenetic analysis, expression in Escherichia coli or Saccharomyces cerevisiae Aspergillus fumigatus
2.5.1.110 expressed in Escherichia coli and Saccharomyces cerevisiae Aspergillus fumigatus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.5.1.100 soluble
-
 Aspergillus fumigatus
-
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.5.1.100 additional information no requirement for divalent metal ions Aspergillus fumigatus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.5.1.100 fumigaclavine A + dimethylallyl diphosphate Aspergillus fumigatus
-
 fumigaclavine C + diphosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.5.1.100 Aspergillus fumigatus
-
 gene fgaPT1
-
2.5.1.110 Aspergillus fumigatus
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.5.1.100 fumigaclavine A + dimethylallyl diphosphate
-
 Aspergillus fumigatus fumigaclavine C + diphosphate
-
 ?
2.5.1.100 fumigaclavine A + dimethylallyl diphosphate the enzyme is specific for dimethylallyl diphosphate as prenyl donor, but shows a broad substrate spectrum for the aromatic substrate, overview Aspergillus fumigatus fumigaclavine C + diphosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.5.1.100 FgaPT1
-
 Aspergillus fumigatus
2.5.1.110 ftmPTS
-
 Aspergillus fumigatus

General Information

EC Number General Information Comment Organism
2.5.1.100 evolution the enzyme belongs to the group of aromatic prenyltransferases Aspergillus fumigatus