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Literature summary extracted from

  • Stivers, J.; Abeygunawardana, C.; Mildvan, A.; Hajipour, G.; Whitman, C.; Chen, L.
    Catalytic role of the amino-terminal proline in 4-oxalocrotonate tautomerase: affinity labeling and heteronuclear NMR studies (1996), Biochemistry, 35, 803-813.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
5.3.2.6 3-Bromopyruvate a active-site-directed irreversible inhibitor, modification of three active sites per hexamer abolishes essentially all activity of the hexamer, pH dependence of inactivation Pseudomonas sp.

Organism

EC Number Organism UniProt Comment Textmining
5.3.2.6 Pseudomonas sp.
-
-
-
5.3.2.6 Pseudomonas sp. CF 600
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.3.2.6 additional information 4-oxalocrotonate tautomerase catalyzes the isomerization of unsaturated 2-oxo acids, converting unconjugated ketones to the conjugated isomers via a dienolic intermediate Pseudomonas sp. ?
-
 ?
5.3.2.6 additional information 4-oxalocrotonate tautomerase catalyzes the isomerization of unsaturated 2-oxo acids, converting unconjugated ketones to the conjugated isomers via a dienolic intermediate Pseudomonas sp. CF 600 ?
-
 ?

Subunits

EC Number Subunits Comment Organism
5.3.2.6 hexamer
-
 Pseudomonas sp.

Synonyms

EC Number Synonyms Comment Organism
5.3.2.6 4-OT
-
 Pseudomonas sp.
5.3.2.6 4-oxalocrotonate tautomerase
-
 Pseudomonas sp.

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
5.3.2.6 23
-
 assay at Pseudomonas sp.

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
5.3.2.6 6.75
-
 assay at Pseudomonas sp.

General Information

EC Number General Information Comment Organism
5.3.2.6 malfunction modification by 3-bromopyruvate of three active sites per hexamer abolishes essentially all activity of the hexamer, spectrocopic and sequence analysis of labeled peptides, overview Pseudomonas sp.