EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
3.4.21.19 | Thermolysin | - |
Staphylococcus aureus | |
3.4.21.19 | thermolysin v8 | - |
Staphylococcus saprophyticus |
EC Number | Cloned (Comment) | Organism |
---|---|---|
3.4.21.19 | expressed in Escherichia coli | Staphylococcus cohnii subsp. cohnii |
3.4.21.19 | expressed in Escherichia coli | Staphylococcus caprae |
EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
3.4.21.19 | N190H/Y192H/S169A | the specific activity of the mutant is 4.5fold increased from that of the wild type enzyme. The mutant potently hydrolyzes LLE-7-amido-4-methylcomarin | Staphylococcus epidermidis |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.4.21.19 | 4-(2-aminoethyl)benzenesulfonyl fluoride | - |
Staphylococcus caprae | |
3.4.21.19 | 4-(2-aminoethyl)benzenesulfonyl fluoride | - |
Staphylococcus cohnii subsp. cohnii | |
3.4.21.19 | diisopropyl fluorophosphate | - |
Staphylococcus caprae | |
3.4.21.19 | diisopropyl fluorophosphate | - |
Staphylococcus cohnii subsp. cohnii | |
3.4.21.19 | additional information | tosyl-L-phenylalanine chloromethyl ketone (0.1 mg/ml), tosyl-L-lysine chloromethyl ketone (50 mg/ml), phenylmethylsulfonyl fluoride (1 mM), aprotinin (0.2 units/ml), leupeptin (0.1 mg/ml), pepstatin (0.01 mg/ml), and dithiothreitol (5 mM) do not inhibit the enzyme activity | Staphylococcus caprae | |
3.4.21.19 | additional information | tosyl-L-phenylalanine chloromethyl ketone (0.1 mg/ml), tosyl-L-lysine chloromethyl ketone (50 mg/ml), phenylmethylsulfonyl fluoride (1 mM), aprotinin (0.2 units/ml), leupeptin (0.1 mg/ml), pepstatin (0.01 mg/ml), and dithiothreitol (5 mM) do not inhibit the enzyme activity | Staphylococcus cohnii subsp. cohnii |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.4.21.19 | Staphylococcus aureus | - |
- |
- |
3.4.21.19 | Staphylococcus aureus ATCC 25923 | - |
- |
- |
3.4.21.19 | Staphylococcus caprae | - |
- |
- |
3.4.21.19 | Staphylococcus caprae GTC 378 | - |
- |
- |
3.4.21.19 | Staphylococcus cohnii subsp. cohnii | - |
- |
- |
3.4.21.19 | Staphylococcus cohnii subsp. cohnii GTC 248 | - |
- |
- |
3.4.21.19 | Staphylococcus epidermidis | - |
- |
- |
3.4.21.19 | Staphylococcus epidermidis ATCC 14990 | - |
- |
- |
3.4.21.19 | Staphylococcus saprophyticus | - |
- |
- |
3.4.21.19 | Staphylococcus warneri | - |
- |
- |
3.4.21.19 | Staphylococcus warneri JCM 2415 | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
3.4.21.19 | Talon affinity column chromatography | Staphylococcus cohnii subsp. cohnii |
3.4.21.19 | Talon affinity column chromatography | Staphylococcus caprae |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.4.21.19 | GluScoh | - |
Staphylococcus cohnii subsp. cohnii |
3.4.21.19 | GluScpr | - |
Staphylococcus caprae |
3.4.21.19 | GluSE | - |
Staphylococcus epidermidis |
3.4.21.19 | GluSsap | - |
Staphylococcus saprophyticus |
3.4.21.19 | GluV8 | - |
Staphylococcus aureus |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
3.4.21.19 | 7.5 | - |
- |
Staphylococcus aureus |
3.4.21.19 | 7.5 | - |
- |
Staphylococcus epidermidis |
3.4.21.19 | 7.5 | - |
- |
Staphylococcus saprophyticus |
3.4.21.19 | 7.5 | - |
- |
Staphylococcus warneri |
3.4.21.19 | 7.5 | - |
- |
Staphylococcus cohnii subsp. cohnii |
3.4.21.19 | 7.5 | - |
- |
Staphylococcus caprae |