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Literature summary extracted from

  • Beste, D.; Bonde, B.; Hawkins, N.; Ward, J.; Beale, M.; Noack, S.; Nöh, K.; Kruger, N.; Ratcliffe, R.; McFadden, J.
    13C metabolic flux analysis identifies an unusual route for pyruvate dissimilation in mycobacteria which requires isocitrate lyase and carbon dioxide fixation (2011), PLoS Pathog., 7, e1002091.
    View publication on PubMedView publication on EuropePMC

Organism

EC Number Organism UniProt Comment Textmining
4.1.3.1 Mycobacterium tuberculosis
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-
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4.1.3.1 Mycobacterium tuberculosis H37Rv
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4.1.3.1 Mycobacterium tuberculosis variant bovis
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-
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Synonyms

EC Number Synonyms Comment Organism
4.1.3.1 isocitrate lyase 1
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 Mycobacterium tuberculosis
4.1.3.1 isocitrate lyase 1
-
 Mycobacterium tuberculosis variant bovis
4.1.3.1 isocitrate lyase 2
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 Mycobacterium tuberculosis variant bovis

General Information

EC Number General Information Comment Organism
4.1.3.1 physiological function involved in a novel pathway for pyruvate dissimilation (GAS pathway: utilizes the glyoxylate shunt, anaplerotic fixation of carbon from CO2 and succinyl CoA synthetase for the generation of succinyl CoA) Mycobacterium tuberculosis
4.1.3.1 physiological function involved in a novel pathway for pyruvate dissimilation (GAS pathway: utilizes the glyoxylate shunt, anaplerotic fixation of carbon from CO2 and succinyl CoA synthetase for the generation of succinyl CoA) Mycobacterium tuberculosis variant bovis