Literature summary extracted from

Zhang, C.; Liu, J.; Zhang, Y.; Cai, X.; Gong, P.; Zhang, J.; Wang, T.; Li, H.; Ye, Z.
Overexpression of SlGMEs leads to ascorbate accumulation with enhanced oxidative stress, cold, and salt tolerance in tomato (2011), Plant Cell Rep., 30, 389-398.

Localization

EC Number	Localization	Comment	Organism	GeneOntology No.	Textmining
5.1.3.18	cytoplasm	-	Solanum lycopersicum	5737	-

Molecular Weight [Da]

EC Number	Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
5.1.3.18	42460	-	isoform GME1, calculated from amino acid sequence	Solanum lycopersicum
5.1.3.18	42550	-	isoform GME2, calculated from amino acid sequence	Solanum lycopersicum

Organism

EC Number	Organism	UniProt	Comment	Textmining
5.1.3.18	Solanum lycopersicum	C6K2K9	isoform GME1; cultivar Ailsa Craig	-
5.1.3.18	Solanum lycopersicum	C6K2L0	isoform GME2; cultivar Ailsa Craig	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
5.1.3.18	flower	-	Solanum lycopersicum	-
5.1.3.18	flower	isoform GME2 transcript content is high in flowers	Solanum lycopersicum	-
5.1.3.18	fruit	-	Solanum lycopersicum	-
5.1.3.18	fruit	isoform GME2 transcript content is low in differential stages of fruits	Solanum lycopersicum	-
5.1.3.18	leaf	-	Solanum lycopersicum	-
5.1.3.18	leaf	isoform GME2 transcript content is high in leaves	Solanum lycopersicum	-
5.1.3.18	root	-	Solanum lycopersicum	-
5.1.3.18	root	isoform GME2 transcript content is low in leaves	Solanum lycopersicum	-
5.1.3.18	stem	-	Solanum lycopersicum	-
5.1.3.18	stem	isoform GME2 transcript content is moderate in leaves	Solanum lycopersicum	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
5.1.3.18	GDP-D-mannose	-	Solanum lycopersicum	GDP-L-galactose	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
5.1.3.18	GDP-mannose 3',5'-epimerase	-	Solanum lycopersicum
5.1.3.18	GME1	isoform	Solanum lycopersicum
5.1.3.18	GME2	isoform	Solanum lycopersicum

General Information

EC Number	General Information	Comment	Organism
5.1.3.18	physiological function	transgenic plants over-expressing isoform GME1 exhibit a significant increase in total ascorbic acid in leaves and red fruits compared with wild type plants and improved tolerance to methyl viologen, cold, and salt stresses	Solanum lycopersicum
5.1.3.18	physiological function	transgenic plants over-expressing isoform GME2 exhibit a significant increase in total ascorbic acid in leaves and red fruits compared with wild type plants and improved tolerance to methyl viologen, cold, and salt stresses	Solanum lycopersicum

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Release 2023.1 (January 2023)