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Literature summary extracted from

  • Dumit, V.I.; Essigke, T.; Cortez, N.; Ullmann, G.M.
    Mechanistic insights into ferredoxin-NADP(H) reductase catalysis involving the conserved glutamate in the active site (2010), J. Mol. Biol., 397, 814-825.
    View publication on PubMed

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.18.1.2 Fe2+ in the iron-sulfur center of ferredoxin Zea mays

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.18.1.2 2 reduced ferredoxin + NADP+ Zea mays
-
 2 oxidized ferredoxin + NADPH + H+
-
 r

Organism

EC Number Organism UniProt Comment Textmining
1.18.1.2 Zea mays
-
-
-

Reaction

EC Number Reaction Comment Organism Reaction ID
1.18.1.2 2 reduced ferredoxin + NADP+ + H+ = 2 oxidized ferredoxin + NADPH FNR is able to transfer electrons between one-electron carriers, ferredoxin or flavodoxin, and two-electron carriers, NADP+ and NADPH, involving its redox cofactor FAD, involvement of Glu312 in the FNR catalytic mechanism not only as a proton donor but also as a key residue for stabilizing and destabilizing reaction intermediates, reaction mechanism and catalytic cycle, overview Zea mays
a

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.18.1.2 2 reduced ferredoxin + NADP+
-
 Zea mays 2 oxidized ferredoxin + NADPH + H+
-
 r

Synonyms

EC Number Synonyms Comment Organism
1.18.1.2 ferredoxin-NADP(H) reductase
-
 Zea mays
1.18.1.2 FNR
-
 Zea mays

Cofactor

EC Number Cofactor Comment Organism Structure
1.18.1.2 FAD noncovalently bound, the flavin can adopt three different redox forms as the oxidized quinone form FAD, the one-electron reduced semiquinone radical form FADHradical, and the fully reduced quinol form FADH2 Zea mays

General Information

EC Number General Information Comment Organism
1.18.1.2 additional information titration behaviour of Glu312, overview Zea mays
1.18.1.2 physiological function in chloroplasts and cyanobacteria, FNR provides the NADPH necessary for photosynthetic CO2 assimilation Zea mays