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Literature summary extracted from
- Escherichia coli arabinose isomerase and Staphylococcus aureus tagatose-6-phosphate isomerase: Which is a better template for directed evolution of non-natural substrate isomerization? (2010), J. Microbiol. Biotechnol., 20, 1018-1021.
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 5.3.1.4 | expressed in Escherichia coli ER2566 cells | Escherichia coli |
Protein Variants
| EC Number | Protein Variants | Comment | Organism |
|---|---|---|---|
| 5.3.1.4 | G270D | the mutation causes a decrease in activity of more than 20% compared to the wild type enzyme | Escherichia coli |
| 5.3.1.4 | L282M | the mutation causes a decrease in activity of more than 20% compared to the wild type enzyme | Escherichia coli |
| 5.3.1.4 | R25C | the mutation causes a decrease in activity of more than 20% compared to the wild type enzyme | Escherichia coli |
| 5.3.1.4 | T451P | the enzyme shows 31% increased activity compared to the wild type enzyme | Escherichia coli |
| 5.3.1.4 | Y496C | the mutation causes a decrease in activity of more than 20% compared to the wild type enzyme | Escherichia coli |
| 5.3.1.26 | D158G | mutation enhances the activity of the enzyme by more than 20% | Staphylococcus aureus |
| 5.3.1.26 | F160S | mutation enhances the activity of the enzyme by more than 20% | Staphylococcus aureus |
| 5.3.1.26 | G132D | mutation enhances the activity of the enzyme by more than 20% | Staphylococcus aureus |
| 5.3.1.26 | V54A | mutation enhances the activity of the enzyme by more than 20% | Staphylococcus aureus |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 5.3.1.26 | additional information | a non-metallic isomerase | Staphylococcus aureus |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 5.3.1.4 | Escherichia coli | - |
- |
- |
| 5.3.1.26 | Staphylococcus aureus | - |
- |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 5.3.1.26 | D-Galactose 6-phosphate | - |
Staphylococcus aureus | D-Tagatose 6-phosphate | - |
? |  |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 5.3.1.26 | tagatose-6-phosphate isomerase | - |
Staphylococcus aureus |
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Release 2023.1 (January 2023)
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