EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.10.3.11 | Escherichia coli | - |
- |
- |
1.10.3.11 | Escherichia coli BW25113 | - |
- |
- |
7.1.1.3 | Escherichia coli | - |
- |
- |
7.1.1.3 | Escherichia coli BW25113 | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.10.3.11 | ubiquinol + O2 | - |
Escherichia coli | ubiquinone + H2O | - |
? | |
1.10.3.11 | ubiquinol + O2 | - |
Escherichia coli BW25113 | ubiquinone + H2O | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.10.3.11 | AppBC | - |
Escherichia coli |
1.10.3.11 | cytochrome bd-II | - |
Escherichia coli |
7.1.1.3 | AppBC | - |
Escherichia coli |
7.1.1.3 | CydAB | - |
Escherichia coli |
7.1.1.3 | cytochrome bd-I quinol oxidase | - |
Escherichia coli |
7.1.1.3 | cytochrome bd-II quinol oxidase | - |
Escherichia coli |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.10.3.11 | heme | the enzyme contains a low spin heme b, high spin heme b, and heme d | Escherichia coli | |
7.1.1.3 | heme | - |
Escherichia coli |
EC Number | Organism | Comment | Expression |
---|---|---|---|
1.10.3.11 | Escherichia coli | cytochrome bd-I-deficient Escherichia coli strain cydB has elevated levels of the AppBC cytochrome bd-II terminal oxidase | up |
EC Number | General Information | Comment | Organism |
---|---|---|---|
1.10.3.11 | physiological function | AppBC alleviates the accumulation of electrons in the quinone pool during respiratory stress via electroneutral ubiquinol oxidation | Escherichia coli |
7.1.1.3 | malfunction | loss of cytochrome bd-I oxidase subunit II (gene cydB) causes diminished respiration rates, impaired motility and enhanced acid resistance. CydB cells contain elevated heme d, particularly at low pH. The GABA/glutamate gadC antiporter is highly up-regulated in cydB cells. Eschrichia coli can compensate for the loss of cytochrome bd-I activity | Escherichia coli |
7.1.1.3 | physiological function | cytochrome bd-II-mediated quinol oxidation prevents the accumulation of NADH, whereas GABA synthesis/antiport maintains the proton motive force for ATP production | Escherichia coli |