EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
4.2.3.56 | Mg2+ | gamma-humulene synthase can utilize Mg2+ or Mn2+ with comparable velocities in the cyclization reaction | Abies grandis | |
4.2.3.56 | Mn2+ | gamma-humulene synthase can utilize Mg2+ or Mn2+ with comparable velocities in the cyclization reaction | Abies grandis | |
4.2.3.56 | additional information | does not utilize K+ in the cyclization reaction | Abies grandis |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
4.2.3.56 | 67940 | - |
calculated from amino acid sequence | Abies grandis |
4.2.3.76 | 67600 | - |
X * 67600, calculated | Abies grandis |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
4.2.3.56 | Abies grandis | O64405 | grand fir | - |
4.2.3.76 | Abies grandis | O64404 | - |
- |
EC Number | Reaction | Comment | Organism | Reaction ID |
---|---|---|---|---|
4.2.3.76 | (2E,6E)-farnesyl diphosphate = (+)-delta-selinene + diphosphate | enzyme utilizes both cisoid and transoid-nerolidyl diphosphate as cyclization intermediates | Abies grandis |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
4.2.3.56 | seed | - |
Abies grandis | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.2.3.56 | (2E,6E)-farnesyl diphosphate | - |
Abies grandis | gamma-humulene + diphosphate | main product with 28.6% yield | ? | |
4.2.3.56 | additional information | gamma-humulene synthase produces mainly gamma-humulene (28.6% yield) from (2E,6E)-farnesyl diphosphate, further products are sibirene (15.1% yield), longifolene (11.8% yield), beta-himachalene (7.2% yield), alpha-himachalene (4.8% yield), beta-bisabolene (3.9% yield), alpha-longipinene (3.4% yield), sativene (3.1% yield), alpha-ylangene (2.7% yield), beta-gurjunene (2.0% yield), gamma-bisabolene (1.9% yield), beta-longipinene (1.5% yield), (E)-beta-farnesene (1.3% yield), (E)-alpha-bisabolene (0.9% yield), delta-amorphene and alpha-amorphene (0.5% yield each), beta-ylangene (0.3% yield), 1,5,9-trimethylcyclododeca-1,5,9-triene and longicyclene (0.2% yield each), as well as beta-cubebene, alpha-copaene, alpha-cubebene, (Z,E)-germacrene B, and cyclosativene (0.1% yield each), along with 26 unknown sesquiterpene olefins (4.1% total yield) | Abies grandis | ? | - |
? | |
4.2.3.76 | (2E,6E)-farnesyl diphosphate | - |
Abies grandis | (+)-delta-selinene + diphosphate | main products are 25.3% delta-selinene, 17.4% (E,E)-germacrene B, 9.7% guaia-6,9-diene, plus 31 further products. Most of the germacrenes produced bear a trans-C2,C3-double bond, revealing the transoid nature of the nerolidyl diphosphate intermediate | ? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
4.2.3.76 | ? | X * 67600, calculated | Abies grandis |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
4.2.3.56 | gamma-humulene synthase | - |
Abies grandis |