Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Hoefnagel, M.H.; Wiskich, J.T.
    Activation of the plant alternative oxidase by high reduction levels of the Q-pool and pyruvate (1998), Arch. Biochem. Biophys., 355, 262-270.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.10.3.11 dithiothreitol
-
 Glycine max
1.10.3.11 dithiothreitol
-
 Arum italicum
1.10.3.11 pyruvate AOX is activated when the ubiquinone-pool becomes highly reduced in the presence of pyruvate. The enzyme is not activated when pyruvate is added after a transient high reduction level of the Q-pool, but is when pyruvate is added before the transient reduction. In the presence of pyruvate, NADH and succinate oxidation can stimulate AOX activity by substituting for dithiothreitol Glycine max
1.10.3.11 pyruvate AOX is activated when the ubiquinone-pool becomes highly reduced in the presence of pyruvate. The enzyme is not activated when pyruvate is added after a transient high reduction level of the Q-pool, but is when pyruvate is added before the transient reduction. In the presence of pyruvate, NADH and succinate oxidation can stimulate AOX activity by substituting for dithiothreitol Arum italicum

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.10.3.11 octyl gallate
-
 Arum italicum
1.10.3.11 octyl gallate
-
 Glycine max
1.10.3.11 ubiquinol AOX is inactivated by its product ubiquinol during catalysis, this inhibition is prevented in the presence of pyruvate. The inhibition can be reversed by a reductive process, achieved by high levels of reduction of the ubiquinone-pool or by dithiothreitol Arum italicum
1.10.3.11 ubiquinol AOX is inactivated by its product ubiquinol during catalysis, this inhibition is prevented in the presence of pyruvate. The inhibition can be reversed by a reductive process, achieved by high levels of reduction of the ubiquinone-pool or by dithiothreitol Glycine max

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.10.3.11 mitochondrion
-
 Glycine max 5739
-
1.10.3.11 mitochondrion
-
 Arum italicum 5739
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.10.3.11 35000
-
 2 * 35000, SDS-PAGE Glycine max
1.10.3.11 35000
-
 2 * 35000, SDS-PAGE Arum italicum

Organism

EC Number Organism UniProt Comment Textmining
1.10.3.11 Arum italicum
-
-
-
1.10.3.11 Glycine max
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.10.3.11 cotyledon
-
 Glycine max
-
1.10.3.11 flower
-
 Arum italicum
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.10.3.11 ubiquinol + O2
-
 Glycine max ubiquinone + H2O
-
 ?
1.10.3.11 ubiquinol + O2
-
 Arum italicum ubiquinone + H2O
-
 ?

Subunits

EC Number Subunits Comment Organism
1.10.3.11 homodimer 2 * 35000, SDS-PAGE Glycine max
1.10.3.11 homodimer 2 * 35000, SDS-PAGE Arum italicum

Synonyms

EC Number Synonyms Comment Organism
1.10.3.11 alternative oxidase
-
 Glycine max
1.10.3.11 alternative oxidase
-
 Arum italicum
1.10.3.11 AOX
-
 Glycine max
1.10.3.11 AOX
-
 Arum italicum