Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Park, S.; Kang, K.; Lee, S.W.; Ahn, M.J.; Bae, J.M.; Back, K.
    Production of serotonin by dual expression of tryptophan decarboxylase and tryptamine 5-hydroxylase in Escherichia coli (2011), Appl. Microbiol. Biotechnol., 89, 1387-1394.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.14.14.186 co-expressed with tryptophan decarboxylase in Escherichia coli BL21(DE3) cells Oryza sativa Japonica Group
4.1.1.105 expressed in Escherichia coli BL21(DE3) cells Catharanthus roseus

General Stability

EC Number General Stability Organism
1.14.14.186 the recombinant N-terminal 37 amino acid deleted enzyme is not functional without glutathione S transferase Oryza sativa Japonica Group

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
4.1.1.105 54000
-
 x * 54000, SDS-PAGE Catharanthus roseus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.14.186 tryptamine + O2 + reduced [NADPH-hemoprotein reductase] Oryza sativa Japonica Group
-
 serotonin + H2O + oxidized [NADPH-hemoprotein reductase]
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.14.186 Oryza sativa Japonica Group Q2QUC5
-
-
4.1.1.105 Catharanthus roseus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.1.1.105 flower
-
 Catharanthus roseus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.14.186 tryptamine + O2 + reduced [NADPH-hemoprotein reductase]
-
 Oryza sativa Japonica Group serotonin + H2O + oxidized [NADPH-hemoprotein reductase]
-
 ?
4.1.1.105 L-tryptophan
-
 Catharanthus roseus tryptamine + CO2
-
 ?

Subunits

EC Number Subunits Comment Organism
4.1.1.105 ? x * 54000, SDS-PAGE Catharanthus roseus

Synonyms

EC Number Synonyms Comment Organism
1.14.14.186 T5H
-
 Oryza sativa Japonica Group
4.1.1.105 TDC
-
 Catharanthus roseus
4.1.1.105 Tryptophan decarboxylase
-
 Catharanthus roseus

Cofactor

EC Number Cofactor Comment Organism Structure
4.1.1.105 pyridoxal 5'-phosphate
-
 Catharanthus roseus