Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Siddique, Y.; Ara, G.; Gupta, J.; Beg, T.; Afzal, M.
    Estimation of cytochrome b5 reductase activity in red blood cells of Rattus norvegicus after the treatment of trichloroacetic acid (2009), Pharmacologyonline, 3, 986-990.
No PubMed abstract available

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.6.2.2 NADH + methemoglobin Rattus norvegicus
-
NAD+ + hemoglobin
-
?

Organism

EC Number Organism UniProt Comment Textmining
1.6.2.2 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.6.2.2 erythrocyte
-
Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.6.2.2 2 ferricytochrome b5 + NADH
-
Rattus norvegicus 2 ferrocytochrome b5 + NAD+ + H+
-
?
1.6.2.2 NADH + methemoglobin
-
Rattus norvegicus NAD+ + hemoglobin
-
?

Synonyms

EC Number Synonyms Comment Organism
1.6.2.2 cytochrome b5 reductase
-
Rattus norvegicus

Cofactor

EC Number Cofactor Comment Organism Structure
1.6.2.2 FAD
-
Rattus norvegicus
1.6.2.2 NADH
-
Rattus norvegicus

Expression

EC Number Organism Comment Expression
1.6.2.2 Rattus norvegicus a significant increase in the activity of cytochrome b5 reductase is observed after trichloroaceticacid treatment at 0.2% (w/v) (about 12 mM) concentration in drinking water ad libitum for 60 days as compared to control groups up

General Information

EC Number General Information Comment Organism
1.6.2.2 physiological function cytochrome b5 reductase is responsible for the reduction of methemoglobin back to hemoglobin Rattus norvegicus