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Literature summary extracted from

  • di Giovanni, M.; Burrone, L.; Baccari, G.; Topo, E.; Santillo, A.
    Distribution of free D-aspartic acid and D-aspartate oxidase in frog Rana esculenta tissues (2010), J. Exp. Zool., 313 A, 137-143.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.4.3.1 additional information
-
 additional information D-AspO kinetics in different tissues, overview Pelophylax lessonae
1.4.3.1 2.85
-
 N-methyl-D-Asp pH 8.2, 37°C, kidney Pelophylax lessonae
1.4.3.1 3.05
-
 N-methyl-D-Asp pH 8.2, 37°C, brain Pelophylax lessonae
1.4.3.1 3.41
-
 N-methyl-D-Asp pH 8.2, 37°C, liver Pelophylax lessonae
1.4.3.1 4.22
-
 D-Asp pH 8.2, 37°C, kidney Pelophylax lessonae
1.4.3.1 4.26
-
 D-Asp pH 8.2, 37°C, brain Pelophylax lessonae
1.4.3.1 4.41
-
 D-Asp pH 8.2, 37°C, liver Pelophylax lessonae
1.4.3.1 6.77
-
 D-Glu pH 8.2, 37°C, kidney Pelophylax lessonae
1.4.3.1 6.91
-
 D-Glu pH 8.2, 37°C, brain Pelophylax lessonae
1.4.3.1 7.52
-
 D-Glu pH 8.2, 37°C, liver Pelophylax lessonae

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.4.3.1 D-Asp + H2O + O2 Pelophylax lessonae
-
 oxaloacetate + NH3 + H2O2
-
 ?
1.4.3.1 D-Glu + H2O + O2 Pelophylax lessonae
-
 2-oxoglutarate + NH3 + H2O2
-
 ?
1.4.3.1 N-methyl-D-Asp + H2O + O2 Pelophylax lessonae
-
 oxaloacetate + methylamine + H2O2
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.4.3.1 Pelophylax lessonae
-
 adult male green frogs
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.4.3.1 brain
-
 Pelophylax lessonae
-
1.4.3.1 harderian gland
-
 Pelophylax lessonae
-
1.4.3.1 kidney
-
 Pelophylax lessonae
-
1.4.3.1 liver
-
 Pelophylax lessonae
-
1.4.3.1 testis
-
 Pelophylax lessonae
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.4.3.1 D-Asp + H2O + O2
-
 Pelophylax lessonae oxaloacetate + NH3 + H2O2
-
 ?
1.4.3.1 D-Glu + H2O + O2
-
 Pelophylax lessonae 2-oxoglutarate + NH3 + H2O2
-
 ?
1.4.3.1 additional information D-AspO activity linearly increases with increasing D-Asp incubation times Pelophylax lessonae ?
-
 ?
1.4.3.1 N-methyl-D-Asp + H2O + O2
-
 Pelophylax lessonae oxaloacetate + methylamine + H2O2
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.4.3.1 D-AspO
-
 Pelophylax lessonae

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
1.4.3.1 37
-
-
 Pelophylax lessonae

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.4.3.1 8.2
-
-
 Pelophylax lessonae

pH Range

EC Number pH Minimum pH Maximum Comment Organism
1.4.3.1 5 9 activity assay range Pelophylax lessonae

Expression

EC Number Organism Comment Expression
1.4.3.1 Pelophylax lessonae D-Asp specifically triggers D-AspO activity up

General Information

EC Number General Information Comment Organism
1.4.3.1 physiological function D-AspO plays an essential role in decreasing excessive amounts of D-Asp in frog tissues Pelophylax lessonae