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Literature summary extracted from

  • Zheng, Y.; Brash, A.R.
    Formation of a cyclopropyl epoxide via a leukotriene A synthase-related pathway in an anaerobic reaction of soybean lipoxygenase-1 with 15S-hydroperoxyeicosatetraenoic acid: evidence that oxygen access is a determinant of secondary reactions with fatty acid hydroperoxides (2010), J. Biol. Chem., 285, 13427-13436.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.13.11.12 NDGA
-
 Glycine max

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.13.11.12 Fe LOX-1 exists in two oxidation states, Fe(II) and Fe(III) Glycine max

Organism

EC Number Organism UniProt Comment Textmining
1.13.11.12 Glycine max
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.13.11.12 (15S)-hydroperoxyeicosatetraenoic acid + O2
-
 Glycine max (8S,15S)-dihydroperoxyeicosatetraenoic acid + (5S,15S)-dihydroperoxyeicosatetraenoic acid
-
 ?
1.13.11.12 linoleate + O2
-
 Glycine max (9Z,11E)-(13S)-13-hydroperoxyoctadeca-9,11-dienoate
-
 ?
1.13.11.12 additional information under anaerobic conditions, LOX-1 shows LTA synthase activity with (15S)-hydroperoxyeicosatetraenoic acid as substrate giving either 14,15-leukotriene A4 or 5,15-dihydroxyeicosatetraenoic acid Glycine max ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.13.11.12 LOX-1
-
 Glycine max