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Literature summary extracted from

  • Yamamoto, M.; Ikeda, T.; Arai, H.; Ishii, M.; Igarashi, Y.
    Carboxylation reaction catalyzed by 2-oxoglutarate:ferredoxin oxidoreductases from Hydrogenobacter thermophilus (2010), Extremophiles, 14, 79-85.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.2.7.3 expression in Escherichia coli Hydrogenobacter thermophilus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.2.7.3 0.00055
-
reduced ferredoxin isozyme Kor, in 10 mM MOPS, pH 6.8, at 70°C Hydrogenobacter thermophilus
1.2.7.3 0.0025
-
reduced ferredoxin isozyme For, in 10 mM MOPS, pH 6.8, at 70°C Hydrogenobacter thermophilus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.2.7.3 succinyl-CoA + CO2 + 2 reduced ferredoxin + 2 H+ Hydrogenobacter thermophilus key enzyme in reductive tricarboxylic acid cycle 2-oxoglutarate + CoA + oxidized ferredoxin
-
?
1.2.7.3 succinyl-CoA + CO2 + 2 reduced ferredoxin + 2 H+ Hydrogenobacter thermophilus TK-6 / IAM 12695 key enzyme in reductive tricarboxylic acid cycle 2-oxoglutarate + CoA + oxidized ferredoxin
-
?

Organism

EC Number Organism UniProt Comment Textmining
1.2.7.3 Hydrogenobacter thermophilus Q93RA3 and Q93RA2 Q93RA3: subunit forA, Q93RA2: subunit forB
-
1.2.7.3 Hydrogenobacter thermophilus Q9AJM0 and Q9AJL9 Q9AJM0: subunit korA, Q9AJL9: subunit korB
-
1.2.7.3 Hydrogenobacter thermophilus TK-6 / IAM 12695 Q93RA3 and Q93RA2 Q93RA3: subunit forA, Q93RA2: subunit forB
-
1.2.7.3 Hydrogenobacter thermophilus TK-6 / IAM 12695 Q9AJM0 and Q9AJL9 Q9AJM0: subunit korA, Q9AJL9: subunit korB
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.2.7.3 2-oxoglutarate + CoA + oxidized ferredoxin
-
Hydrogenobacter thermophilus succinyl-CoA + CO2 + 2 reduced ferredoxin + 2 H+
-
r
1.2.7.3 2-oxoglutarate + CoA + oxidized ferredoxin
-
Hydrogenobacter thermophilus TK-6 / IAM 12695 succinyl-CoA + CO2 + 2 reduced ferredoxin + 2 H+
-
r
1.2.7.3 succinyl-CoA + CO2 + 2 reduced ferredoxin + 2 H+
-
Hydrogenobacter thermophilus 2-oxoglutarate + CoA + oxidized ferredoxin
-
r
1.2.7.3 succinyl-CoA + CO2 + 2 reduced ferredoxin + 2 H+ key enzyme in reductive tricarboxylic acid cycle Hydrogenobacter thermophilus 2-oxoglutarate + CoA + oxidized ferredoxin
-
?
1.2.7.3 succinyl-CoA + CO2 + 2 reduced ferredoxin + 2 H+
-
Hydrogenobacter thermophilus TK-6 / IAM 12695 2-oxoglutarate + CoA + oxidized ferredoxin
-
r
1.2.7.3 succinyl-CoA + CO2 + 2 reduced ferredoxin + 2 H+ key enzyme in reductive tricarboxylic acid cycle Hydrogenobacter thermophilus TK-6 / IAM 12695 2-oxoglutarate + CoA + oxidized ferredoxin
-
?

Synonyms

EC Number Synonyms Comment Organism
1.2.7.3 2-oxoglutarate:ferredoxin oxidoreductase
-
Hydrogenobacter thermophilus
1.2.7.3 For(OGOR)
-
Hydrogenobacter thermophilus
1.2.7.3 Kor(OGOR)
-
Hydrogenobacter thermophilus
1.2.7.3 OGOR
-
Hydrogenobacter thermophilus