EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.13.11.12 | 2-(3,4-dihydroxybenzoyl)-2,4,6-trihydroxybenzofuran-3(2H)-one | quercetin is slowly oxidized by hydroperoxides to a rather stable intermediate, 2-(3,4-dihydroxybenzoyl)-2,4,6-trihydroxybenzofuran-3(2H)-one, which still inhibits the enzymatic oxidation, probably as a chelator | Glycine max | |
1.13.11.12 | kaempferol | - |
Glycine max | |
1.13.11.12 | additional information | 3,4-dihydro-7-hydroxycadalin, 7-hydroxycadalin, 3-hydroxyphenylacetic acid, 4-hydroxy-3-methoxyphenylacetic acid, and 3,4-dihydroxyphenylacetic acid do not inhibit the soybean lipoxygenase-1 catalyzed lipid peroxidation | Glycine max | |
1.13.11.12 | quercetin | noncompetitive inhibition by initially reducing the ferric form of the enzyme to an inactive ferrous form | Glycine max | |
1.13.11.12 | rutin | - |
Glycine max |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.13.11.12 | Glycine max | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.13.11.12 | linoleate + O2 | - |
Glycine max | (9Z,11E)-(13S)-13-hydroperoxyoctadeca-9,11-dienoate | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.13.11.12 | lipoxygenase-1 | - |
Glycine max |
EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|---|
1.13.11.12 | 0.0048 | - |
in 0.1M Tris-HCl (pH 8.0), at 25°C | Glycine max | quercetin |