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Literature summary extracted from

  • Chimenti, F.; Secci, D.; Bolasco, A.; Chimenti, P.; Granese, A.; Carradori, S.; Maccioni, E.; Cardia, M.C.; Yanez, M.; Orallo, F.; Alcaro, S.; Ortuso, F.; Cirilli, R.; Ferretti, R.; Distinto, S.; Kirchmair, J.; Langer, T.
    Synthesis, semipreparative HPLC separation, biological evaluation, and 3D-QSAR of hydrazothiazole derivatives as human monoamine oxidase B inhibitors (2010), Bioorg. Med. Chem., 18, 5063-5070.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.4.3.4 expression of hMAO-A and hMAO-B in insect cells BTI-TN-5B1-4 using the baculovirus infection system Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.4.3.4 (R)-2-[(2E)-2-(2-methylcyclohexylidene)hydrazinyl]-4-(4-nitrophenyl)-1,3-thiazole
-
Homo sapiens
1.4.3.4 (R)-4-(2,4-difluorophenyl)-2-[(2E)-2-(2-methylcyclohexylidene)hydrazinyl]-1,3-thiazole
-
Homo sapiens
1.4.3.4 (R)-4-(4-fluorophenyl)-2-[(2E)-2-(2-methylcyclohexylidene)hydrazinyl]-1,3-thiazole
-
Homo sapiens
1.4.3.4 (R)-4-[2-[(2E)-2-(2-methylcyclohexylidene)hydrazinyl]-1,3-thiazol-4-yl]benzonitrile
-
Homo sapiens
1.4.3.4 (S)-2-[(2E)-2-(2-methylcyclohexylidene)hydrazinyl]-4-(4-nitrophenyl)-1,3-thiazole
-
Homo sapiens
1.4.3.4 (S)-4-(2,4-difluorophenyl)-2-[(2E)-2-(2-methylcyclohexylidene)hydrazinyl]-1,3-thiazole
-
Homo sapiens
1.4.3.4 (S)-4-(4-fluorophenyl)-2-[(2E)-2-(2-methylcyclohexylidene)hydrazinyl]-1,3-thiazole
-
Homo sapiens
1.4.3.4 (S)-4-[2-[(2E)-2-(2-methylcyclohexylidene)hydrazinyl]-1,3-thiazol-4-yl]benzonitrile
-
Homo sapiens
1.4.3.4 2-(2-cycloheptylidenehydrazinyl)-4-(2,4-dichlorophenyl)-1,3-thiazole
-
Homo sapiens
1.4.3.4 2-(2-cycloheptylidenehydrazinyl)-4-(2,4-difluorophenyl)-1,3-thiazole
-
Homo sapiens
1.4.3.4 2-(2-cycloheptylidenehydrazinyl)-4-(4-fluorophenyl)-1,3-thiazole
-
Homo sapiens
1.4.3.4 2-(2-cycloheptylidenehydrazinyl)-4-(4-methoxyphenyl)-1,3-thiazole
-
Homo sapiens
1.4.3.4 2-(2-cycloheptylidenehydrazinyl)-4-(4-methylphenyl)-1,3-thiazole
-
Homo sapiens
1.4.3.4 2-(2-cycloheptylidenehydrazinyl)-4-(4-nitrophenyl)-1,3-thiazole
-
Homo sapiens
1.4.3.4 2-(2-cycloheptylidenehydrazinyl)-4-phenyl-1,3-thiazole
-
Homo sapiens
1.4.3.4 2-(2-cyclohexylidenehydrazinyl)-4-(2,4-difluorophenyl)-1,3-thiazole
-
Homo sapiens
1.4.3.4 2-(2-cyclohexylidenehydrazinyl)-4-(4-fluorophenyl)-1,3-thiazole
-
Homo sapiens
1.4.3.4 2-(2-cyclohexylidenehydrazinyl)-4-(4-methoxyphenyl)-1,3-thiazole
-
Homo sapiens
1.4.3.4 2-(2-cyclohexylidenehydrazinyl)-4-(4-methylphenyl)-1,3-thiazole
-
Homo sapiens
1.4.3.4 2-(2-cyclohexylidenehydrazinyl)-4-(4-nitrophenyl)-1,3-thiazole
-
Homo sapiens
1.4.3.4 2-(2-cyclohexylidenehydrazinyl)-4-phenyl-1,3-thiazole
-
Homo sapiens
1.4.3.4 2-(2-cyclopentylidenehydrazinyl)-4-(2,4-dichlorophenyl)-1,3-thiazole
-
Homo sapiens
1.4.3.4 2-(2-cyclopentylidenehydrazinyl)-4-(2,4-difluorophenyl)-1,3-thiazole
-
Homo sapiens
1.4.3.4 2-(2-cyclopentylidenehydrazinyl)-4-(4-fluorophenyl)-1,3-thiazole
-
Homo sapiens
1.4.3.4 2-(2-cyclopentylidenehydrazinyl)-4-(4-methoxyphenyl)-1,3-thiazole
-
Homo sapiens
1.4.3.4 2-(2-cyclopentylidenehydrazinyl)-4-(4-methylphenyl)-1,3-thiazole
-
Homo sapiens
1.4.3.4 2-(2-cyclopentylidenehydrazinyl)-4-(4-nitrophenyl)-1,3-thiazole
-
Homo sapiens
1.4.3.4 2-(2-cyclopentylidenehydrazinyl)-4-phenyl-1,3-thiazole
-
Homo sapiens
1.4.3.4 2-[(2E)-2-(2-methylcyclohexylidene)hydrazinyl]-4-(4-methylphenyl)-1,3-thiazole
-
Homo sapiens
1.4.3.4 2-[(2E)-2-(2-methylcyclohexylidene)hydrazinyl]-4-(4-nitrophenyl)-1,3-thiazole
-
Homo sapiens
1.4.3.4 2-[(2E)-2-(2-methylcyclohexylidene)hydrazinyl]-4-phenyl-1,3-thiazole
-
Homo sapiens
1.4.3.4 2-[2-(4-methylcyclohexylidene)hydrazinyl]-4-(4-methylphenyl)-1,3-thiazole
-
Homo sapiens
1.4.3.4 2-[2-(4-methylcyclohexylidene)hydrazinyl]-4-(4-nitrophenyl)-1,3-thiazole
-
Homo sapiens
1.4.3.4 2-[2-(4-methylcyclohexylidene)hydrazinyl]-4-phenyl-1,3-thiazole
-
Homo sapiens
1.4.3.4 4-(2,4-dichlorophenyl)-2-[(2E)-2-(2-methylcyclohexylidene)hydrazinyl]-1,3-thiazole
-
Homo sapiens
1.4.3.4 4-(2,4-dichlorophenyl)-2-[2-(4-methylcyclohexylidene)hydrazinyl]-1,3-thiazole
-
Homo sapiens
1.4.3.4 4-(2,4-difluorophenyl)-2-[(2E)-2-(2-methylcyclohexylidene)hydrazinyl]-1,3-thiazole
-
Homo sapiens
1.4.3.4 4-(2,4-difluorophenyl)-2-[2-(4-methylcyclohexylidene)hydrazinyl]-1,3-thiazole
-
Homo sapiens
1.4.3.4 4-(4-chlorophenyl)-2-(2-cycloheptylidenehydrazinyl)-1,3-thiazole
-
Homo sapiens
1.4.3.4 4-(4-chlorophenyl)-2-(2-cyclohexylidenehydrazinyl)-1,3-thiazole
-
Homo sapiens
1.4.3.4 4-(4-chlorophenyl)-2-(2-cyclopentylidenehydrazinyl)-1,3-thiazole
-
Homo sapiens
1.4.3.4 4-(4-chlorophenyl)-2-[(2E)-2-(2-methylcyclohexylidene)hydrazinyl]-1,3-thiazole
-
Homo sapiens
1.4.3.4 4-(4-chlorophenyl)-2-[2-(4-methylcyclohexylidene)hydrazinyl]-1,3-thiazole
-
Homo sapiens
1.4.3.4 4-(4-fluorophenyl)-2-[(2E)-2-(2-methylcyclohexylidene)hydrazinyl]-1,3-thiazole
-
Homo sapiens
1.4.3.4 4-(4-fluorophenyl)-2-[2-(4-methylcyclohexylidene)hydrazinyl]-1,3-thiazole
-
Homo sapiens
1.4.3.4 4-(4-methoxyphenyl)-2-[(2E)-2-(2-methylcyclohexylidene)hydrazinyl]-1,3-thiazole
-
Homo sapiens
1.4.3.4 4-(4-methoxyphenyl)-2-[2-(4-methylcyclohexylidene)hydrazinyl]-1,3-thiazole
-
Homo sapiens
1.4.3.4 4-[2-(2-cycloheptylidenehydrazinyl)-1,3-thiazol-4-yl]benzonitrile
-
Homo sapiens
1.4.3.4 4-[2-(2-cyclohexylidenehydrazinyl)-1,3-thiazol-4-yl]benzonitrile
-
Homo sapiens
1.4.3.4 4-[2-(2-cyclopentylidenehydrazinyl)-1,3-thiazol-4-yl]benzonitrile
-
Homo sapiens
1.4.3.4 4-[2-[(2E)-2-(2-methylcyclohexylidene)hydrazinyl]-1,3-thiazol-4-yl]benzonitrile
-
Homo sapiens
1.4.3.4 4-[2-[2-(4-methylcyclohexylidene)hydrazinyl]-1,3-thiazol-4-yl]benzonitrile
-
Homo sapiens
1.4.3.4 brofaromine
-
Homo sapiens
1.4.3.4 Clorgyline
-
Homo sapiens
1.4.3.4 Iproniazide
-
Homo sapiens
1.4.3.4 isocarboxazide
-
Homo sapiens
1.4.3.4 lazabemide
-
Homo sapiens
1.4.3.4 moclobemide
-
Homo sapiens
1.4.3.4 additional information cycloalkylidenhydrazothiazole derivative inhibitors derived from N1-thiocarbamoyl-3,5-diaryl-4,5-dihydro-(1H)-pyrazole, molecular modeling, overview. No inhibition by 13, 42, and 44 Homo sapiens
1.4.3.4 N-(cycloheptylidenemethyl)-4-(3-methoxyphenyl)-1,3-thiazol-2-amine
-
Homo sapiens
1.4.3.4 Pargyline
-
Homo sapiens
1.4.3.4 R-(-)-deprenyl
-
Homo sapiens
1.4.3.4 R-rasagiline
-
Homo sapiens
1.4.3.4 toloxatone
-
Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.4.3.4 mitochondrial outer membrane tightly bound Homo sapiens 5741
-

Organism

EC Number Organism UniProt Comment Textmining
1.4.3.4 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.4.3.4 kidney
-
Homo sapiens
-
1.4.3.4 liver
-
Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.4.3.4 4-tyramine + H2O + O2 substrate for both hMAO-A and hMAO-B Homo sapiens ?
-
?

Synonyms

EC Number Synonyms Comment Organism
1.4.3.4 MAO-A
-
Homo sapiens
1.4.3.4 MAO-B
-
Homo sapiens
1.4.3.4 monoamine oxidase B
-
Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
1.4.3.4 FAD
-
Homo sapiens

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
1.4.3.4 0.000003
-
MAO B, pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-(2-cyclopentylidenehydrazinyl)-4-(2,4-difluorophenyl)-1,3-thiazole
1.4.3.4 0.000004
-
MAO B, pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-(2-cyclohexylidenehydrazinyl)-4-(4-fluorophenyl)-1,3-thiazole
1.4.3.4 0.000004
-
MAO B, pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-(2-cycloheptylidenehydrazinyl)-4-(4-fluorophenyl)-1,3-thiazole
1.4.3.4 0.000011
-
MAO B, pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-(2-cycloheptylidenehydrazinyl)-4-(4-nitrophenyl)-1,3-thiazole
1.4.3.4 0.000014
-
MAO B, pH not specified in the publication, temperature not specified in the publication Homo sapiens 4-(2,4-difluorophenyl)-2-[(2E)-2-(2-methylcyclohexylidene)hydrazinyl]-1,3-thiazole
1.4.3.4 0.000016
-
MAO B, pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-(2-cycloheptylidenehydrazinyl)-4-(2,4-difluorophenyl)-1,3-thiazole
1.4.3.4 0.000026
-
MAO B, pH not specified in the publication, temperature not specified in the publication Homo sapiens 4-[2-[(2E)-2-(2-methylcyclohexylidene)hydrazinyl]-1,3-thiazol-4-yl]benzonitrile
1.4.3.4 0.000027
-
MAO B, pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-(2-cycloheptylidenehydrazinyl)-4-phenyl-1,3-thiazole
1.4.3.4 0.000032
-
MAO B, pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-[(2E)-2-(2-methylcyclohexylidene)hydrazinyl]-4-(4-nitrophenyl)-1,3-thiazole
1.4.3.4 0.00004
-
MAO B, pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-(2-cyclopentylidenehydrazinyl)-4-(4-fluorophenyl)-1,3-thiazole
1.4.3.4 0.000043
-
MAO B, pH not specified in the publication, temperature not specified in the publication Homo sapiens 4-(4-fluorophenyl)-2-[2-(4-methylcyclohexylidene)hydrazinyl]-1,3-thiazole
1.4.3.4 0.000046
-
MAO B, pH not specified in the publication, temperature not specified in the publication Homo sapiens 4-[2-(2-cycloheptylidenehydrazinyl)-1,3-thiazol-4-yl]benzonitrile
1.4.3.4 0.000053
-
MAO B, pH not specified in the publication, temperature not specified in the publication Homo sapiens 4-[2-(2-cyclohexylidenehydrazinyl)-1,3-thiazol-4-yl]benzonitrile
1.4.3.4 0.000061
-
MAO B, pH not specified in the publication, temperature not specified in the publication Homo sapiens 4-[2-[2-(4-methylcyclohexylidene)hydrazinyl]-1,3-thiazol-4-yl]benzonitrile
1.4.3.4 0.000086
-
MAO B, pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-(2-cyclohexylidenehydrazinyl)-4-(4-nitrophenyl)-1,3-thiazole
1.4.3.4 0.000091
-
MAO B, pH not specified in the publication, temperature not specified in the publication Homo sapiens 4-(2,4-difluorophenyl)-2-[2-(4-methylcyclohexylidene)hydrazinyl]-1,3-thiazole
1.4.3.4 0.000094
-
MAO B, pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-(2-cyclopentylidenehydrazinyl)-4-(4-nitrophenyl)-1,3-thiazole
1.4.3.4 0.000116
-
MAO B, pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-(2-cyclohexylidenehydrazinyl)-4-phenyl-1,3-thiazole
1.4.3.4 0.000134
-
MAO B, pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-(2-cyclopentylidenehydrazinyl)-4-(4-methylphenyl)-1,3-thiazole
1.4.3.4 0.000143
-
MAO B, pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-[(2E)-2-(2-methylcyclohexylidene)hydrazinyl]-4-(4-methylphenyl)-1,3-thiazole
1.4.3.4 0.000164
-
MAO B, pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-(2-cyclopentylidenehydrazinyl)-4-(4-methoxyphenyl)-1,3-thiazole
1.4.3.4 0.0001752
-
MAO A, pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-(2-cyclohexylidenehydrazinyl)-4-(4-fluorophenyl)-1,3-thiazole
1.4.3.4 0.000202
-
MAO B, pH not specified in the publication, temperature not specified in the publication Homo sapiens N-(cycloheptylidenemethyl)-4-(3-methoxyphenyl)-1,3-thiazol-2-amine
1.4.3.4 0.000204
-
MAO B, pH not specified in the publication, temperature not specified in the publication Homo sapiens 4-(4-fluorophenyl)-2-[(2E)-2-(2-methylcyclohexylidene)hydrazinyl]-1,3-thiazole
1.4.3.4 0.000211
-
MAO B, pH not specified in the publication, temperature not specified in the publication Homo sapiens 4-(4-chlorophenyl)-2-(2-cyclohexylidenehydrazinyl)-1,3-thiazole
1.4.3.4 0.000221
-
MAO B, pH not specified in the publication, temperature not specified in the publication Homo sapiens 4-[2-(2-cyclopentylidenehydrazinyl)-1,3-thiazol-4-yl]benzonitrile
1.4.3.4 0.000259
-
MAO B, pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-[2-(4-methylcyclohexylidene)hydrazinyl]-4-phenyl-1,3-thiazole
1.4.3.4 0.000262
-
MAO B, pH not specified in the publication, temperature not specified in the publication Homo sapiens 4-(4-chlorophenyl)-2-(2-cyclopentylidenehydrazinyl)-1,3-thiazole
1.4.3.4 0.000284
-
MAO B, pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-(2-cyclopentylidenehydrazinyl)-4-(2,4-dichlorophenyl)-1,3-thiazole
1.4.3.4 0.000296
-
MAO B, pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-(2-cyclopentylidenehydrazinyl)-4-phenyl-1,3-thiazole
1.4.3.4 0.000344
-
MAO A, pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-(2-cyclopentylidenehydrazinyl)-4-(4-nitrophenyl)-1,3-thiazole
1.4.3.4 0.000362
-
MAO B, pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-[2-(4-methylcyclohexylidene)hydrazinyl]-4-(4-nitrophenyl)-1,3-thiazole
1.4.3.4 0.000477
-
MAO B, pH not specified in the publication, temperature not specified in the publication Homo sapiens 4-(4-chlorophenyl)-2-(2-cycloheptylidenehydrazinyl)-1,3-thiazole
1.4.3.4 0.000644
-
MAO A, pH not specified in the publication, temperature not specified in the publication Homo sapiens 4-[2-(2-cyclopentylidenehydrazinyl)-1,3-thiazol-4-yl]benzonitrile
1.4.3.4 0.000652
-
MAO B, pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-(2-cyclohexylidenehydrazinyl)-4-(2,4-difluorophenyl)-1,3-thiazole
1.4.3.4 0.000711
-
MAO B, pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-[(2E)-2-(2-methylcyclohexylidene)hydrazinyl]-4-phenyl-1,3-thiazole
1.4.3.4 0.00092
-
MAO B, pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-(2-cycloheptylidenehydrazinyl)-4-(4-methylphenyl)-1,3-thiazole
1.4.3.4 0.00094
-
MAO B, pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-(2-cycloheptylidenehydrazinyl)-4-(2,4-dichlorophenyl)-1,3-thiazole
1.4.3.4 0.001055
-
MAO A, pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-(2-cyclopentylidenehydrazinyl)-4-(4-methoxyphenyl)-1,3-thiazole
1.4.3.4 0.002019
-
MAO A, pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-(2-cyclopentylidenehydrazinyl)-4-(4-methylphenyl)-1,3-thiazole
1.4.3.4 0.002318
-
MAO A, pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-(2-cyclopentylidenehydrazinyl)-4-(2,4-difluorophenyl)-1,3-thiazole
1.4.3.4 0.002373
-
MAO B, pH not specified in the publication, temperature not specified in the publication Homo sapiens 4-(4-methoxyphenyl)-2-[(2E)-2-(2-methylcyclohexylidene)hydrazinyl]-1,3-thiazole
1.4.3.4 0.002411
-
MAO B, pH not specified in the publication, temperature not specified in the publication Homo sapiens 4-(4-chlorophenyl)-2-[2-(4-methylcyclohexylidene)hydrazinyl]-1,3-thiazole
1.4.3.4 0.002762
-
MAO A, pH not specified in the publication, temperature not specified in the publication Homo sapiens 4-(4-methoxyphenyl)-2-[(2E)-2-(2-methylcyclohexylidene)hydrazinyl]-1,3-thiazole
1.4.3.4 0.002911
-
MAO A, pH not specified in the publication, temperature not specified in the publication Homo sapiens 4-(4-chlorophenyl)-2-(2-cyclohexylidenehydrazinyl)-1,3-thiazole
1.4.3.4 0.003689
-
MAO B, pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-(2-cyclohexylidenehydrazinyl)-4-(4-methylphenyl)-1,3-thiazole
1.4.3.4 0.003925
-
MAO A, pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-(2-cycloheptylidenehydrazinyl)-4-(4-methoxyphenyl)-1,3-thiazole
1.4.3.4 0.004327
-
MAO A, pH not specified in the publication, temperature not specified in the publication Homo sapiens 4-[2-(2-cycloheptylidenehydrazinyl)-1,3-thiazol-4-yl]benzonitrile
1.4.3.4 0.004436
-
MAO A, pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-(2-cyclopentylidenehydrazinyl)-4-(4-fluorophenyl)-1,3-thiazole
1.4.3.4 0.004837
-
MAO A, pH not specified in the publication, temperature not specified in the publication Homo sapiens 4-[2-(2-cyclohexylidenehydrazinyl)-1,3-thiazol-4-yl]benzonitrile
1.4.3.4 0.005025
-
MAO B, pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-(2-cycloheptylidenehydrazinyl)-4-(4-methoxyphenyl)-1,3-thiazole
1.4.3.4 0.005477
-
MAO B, pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-[2-(4-methylcyclohexylidene)hydrazinyl]-4-(4-methylphenyl)-1,3-thiazole
1.4.3.4 0.005763
-
MAO A, pH not specified in the publication, temperature not specified in the publication Homo sapiens 4-(4-methoxyphenyl)-2-[2-(4-methylcyclohexylidene)hydrazinyl]-1,3-thiazole
1.4.3.4 0.006182
-
MAO A, pH not specified in the publication, temperature not specified in the publication Homo sapiens 4-(4-chlorophenyl)-2-(2-cycloheptylidenehydrazinyl)-1,3-thiazole
1.4.3.4 0.006994
-
MAO A, pH not specified in the publication, temperature not specified in the publication Homo sapiens 4-[2-[2-(4-methylcyclohexylidene)hydrazinyl]-1,3-thiazol-4-yl]benzonitrile
1.4.3.4 0.00716
-
MAO A, pH not specified in the publication, temperature not specified in the publication Homo sapiens 4-(4-chlorophenyl)-2-(2-cyclopentylidenehydrazinyl)-1,3-thiazole
1.4.3.4 0.007229
-
MAO A, pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-(2-cycloheptylidenehydrazinyl)-4-(2,4-difluorophenyl)-1,3-thiazole
1.4.3.4 0.007509
-
MAO A, pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-(2-cyclohexylidenehydrazinyl)-4-(4-methoxyphenyl)-1,3-thiazole
1.4.3.4 0.007883
-
MAO A, pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-(2-cyclopentylidenehydrazinyl)-4-phenyl-1,3-thiazole
1.4.3.4 0.008109
-
MAO A, pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-[2-(4-methylcyclohexylidene)hydrazinyl]-4-(4-methylphenyl)-1,3-thiazole
1.4.3.4 0.009446
-
MAO B, pH not specified in the publication, temperature not specified in the publication Homo sapiens 4-(2,4-dichlorophenyl)-2-[2-(4-methylcyclohexylidene)hydrazinyl]-1,3-thiazole
1.4.3.4 0.009612
-
MAO A, pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-(2-cycloheptylidenehydrazinyl)-4-(4-methylphenyl)-1,3-thiazole
1.4.3.4 0.01028
-
MAO A, pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-(2-cycloheptylidenehydrazinyl)-4-(4-fluorophenyl)-1,3-thiazole
1.4.3.4 0.01196
-
MAO B, pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-(2-cyclohexylidenehydrazinyl)-4-(4-methoxyphenyl)-1,3-thiazole
1.4.3.4 0.01313
-
MAO B, pH not specified in the publication, temperature not specified in the publication Homo sapiens 4-(4-chlorophenyl)-2-[(2E)-2-(2-methylcyclohexylidene)hydrazinyl]-1,3-thiazole
1.4.3.4 0.01485
-
MAO A, pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-(2-cycloheptylidenehydrazinyl)-4-phenyl-1,3-thiazole
1.4.3.4 0.01522
-
MAO A, pH not specified in the publication, temperature not specified in the publication Homo sapiens 4-(4-chlorophenyl)-2-[2-(4-methylcyclohexylidene)hydrazinyl]-1,3-thiazole
1.4.3.4 0.01785
-
MAO A, pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-(2-cycloheptylidenehydrazinyl)-4-(4-nitrophenyl)-1,3-thiazole
1.4.3.4 0.0195
-
MAO A, pH not specified in the publication, temperature not specified in the publication Homo sapiens 4-(2,4-difluorophenyl)-2-[2-(4-methylcyclohexylidene)hydrazinyl]-1,3-thiazole
1.4.3.4 0.02088
-
MAO A, pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-[2-(4-methylcyclohexylidene)hydrazinyl]-4-(4-nitrophenyl)-1,3-thiazole
1.4.3.4 0.02373
-
MAO A, pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-(2-cyclohexylidenehydrazinyl)-4-(4-methylphenyl)-1,3-thiazole
1.4.3.4 0.02415
-
MAO A, pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-(2-cyclohexylidenehydrazinyl)-4-(4-nitrophenyl)-1,3-thiazole
1.4.3.4 0.02681
-
MAO B, pH not specified in the publication, temperature not specified in the publication Homo sapiens 4-(2,4-dichlorophenyl)-2-[(2E)-2-(2-methylcyclohexylidene)hydrazinyl]-1,3-thiazole
1.4.3.4 0.03103
-
MAO A, pH not specified in the publication, temperature not specified in the publication Homo sapiens 4-[2-[(2E)-2-(2-methylcyclohexylidene)hydrazinyl]-1,3-thiazol-4-yl]benzonitrile
1.4.3.4 0.0312
-
MAO B, pH not specified in the publication, temperature not specified in the publication Homo sapiens 4-(4-methoxyphenyl)-2-[2-(4-methylcyclohexylidene)hydrazinyl]-1,3-thiazole
1.4.3.4 0.03422
-
MAO A, pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-[2-(4-methylcyclohexylidene)hydrazinyl]-4-phenyl-1,3-thiazole
1.4.3.4 0.03522
-
MAO A, pH not specified in the publication, temperature not specified in the publication Homo sapiens 4-(4-chlorophenyl)-2-[(2E)-2-(2-methylcyclohexylidene)hydrazinyl]-1,3-thiazole
1.4.3.4 0.03796
-
MAO A, pH not specified in the publication, temperature not specified in the publication Homo sapiens 4-(2,4-difluorophenyl)-2-[(2E)-2-(2-methylcyclohexylidene)hydrazinyl]-1,3-thiazole
1.4.3.4 0.04124
-
MAO A, pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-[(2E)-2-(2-methylcyclohexylidene)hydrazinyl]-4-phenyl-1,3-thiazole
1.4.3.4 0.04356
-
MAO A, pH not specified in the publication, temperature not specified in the publication Homo sapiens 4-(4-fluorophenyl)-2-[(2E)-2-(2-methylcyclohexylidene)hydrazinyl]-1,3-thiazole
1.4.3.4 0.0447
-
MAO A, pH not specified in the publication, temperature not specified in the publication Homo sapiens 4-(2,4-dichlorophenyl)-2-[(2E)-2-(2-methylcyclohexylidene)hydrazinyl]-1,3-thiazole
1.4.3.4 0.04546
-
MAO A, pH not specified in the publication, temperature not specified in the publication Homo sapiens 4-(4-fluorophenyl)-2-[2-(4-methylcyclohexylidene)hydrazinyl]-1,3-thiazole
1.4.3.4 0.04575
-
MAO A, pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-(2-cyclohexylidenehydrazinyl)-4-(2,4-difluorophenyl)-1,3-thiazole
1.4.3.4 0.04835
-
MAO A, pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-(2-cyclohexylidenehydrazinyl)-4-phenyl-1,3-thiazole
1.4.3.4 0.05451
-
MAO A, pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-(2-cyclopentylidenehydrazinyl)-4-(2,4-dichlorophenyl)-1,3-thiazole
1.4.3.4 0.05928
-
MAO A, pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-(2-cycloheptylidenehydrazinyl)-4-(2,4-dichlorophenyl)-1,3-thiazole
1.4.3.4 0.08149
-
MAO A, pH not specified in the publication, temperature not specified in the publication Homo sapiens 4-(2,4-dichlorophenyl)-2-[2-(4-methylcyclohexylidene)hydrazinyl]-1,3-thiazole