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Literature summary extracted from

  • Bernstein, H.G.; Derst, C.; Stich, C.; Pruess, H.; Peters, D.; Krauss, M.; Bogerts, B.; Veh, R.W.; Laube, G.
    The agmatine-degrading enzyme agmatinase: a key to agmatine signaling in rat and human brain? (2010), Amino Acids, 40, 453-465.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.5.3.11 agmatine + H2O Homo sapiens
-
 putrescine + urea
-
 ?
3.5.3.11 agmatine + H2O Rattus norvegicus
-
 putrescine + urea
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.5.3.11 Homo sapiens
-
-
-
3.5.3.11 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.5.3.11 brain
-
 Homo sapiens
-
3.5.3.11 brain
-
 Rattus norvegicus
-
3.5.3.11 neuron agmatinase is predominantly detected in distinct populations of neurons, especially cortical interneurons. Principal neurons in limbic regions like the habenula and in the cerebellum robustly express agmatinase protein Homo sapiens
-
3.5.3.11 neuron agmatinase is predominantly detected in distinct populations of neurons, especially cortical interneurons. Principal neurons in limbic regions like the habenula and in the cerebellum robustly express agmatinase protein Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.5.3.11 agmatine + H2O
-
 Homo sapiens putrescine + urea
-
 ?
3.5.3.11 agmatine + H2O
-
 Rattus norvegicus putrescine + urea
-
 ?