Literature summary extracted from

Osman, D.; Gobert, V.; Ponthan, F.; Heidenreich, O.; Haenlin, M.; Waltzer, L.
A Drosophila model identifies calpains as modulators of the human leukemogenic fusion protein AML1-ETO (2009), Proc. Natl. Acad. Sci. USA, 106, 12043-12048.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
3.4.22.B37	carbobenzoxy-valinyl-phenylalaninal	-	Drosophila melanogaster
3.4.22.B37	N-acetyl-leucyl-leucyl-norleucinal	-	Drosophila melanogaster

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.4.22.B37	Drosophila melanogaster	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
3.4.22.B37	hemocyte	-	Drosophila melanogaster	-

Synonyms

EC Number	Synonyms	Comment	Organism
3.4.22.B37	calpainB	-	Drosophila melanogaster

General Information

EC Number	General Information	Comment	Organism
3.4.22.B37	physiological function	calpainB is required for acute myeloid leukemia 1-ETO-induced blood cell disorders in Drosophila	Drosophila melanogaster

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Release 2023.1 (January 2023)