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Literature summary extracted from
- Inflammatory stimuli regulate caspase substrate profiles (2010), Mol. Cell. Proteomics, 9, 880-893.
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.22.36 | ATP | - |
Homo sapiens |  |
| 3.4.22.36 | lipopolysaccharide | - |
Homo sapiens | |
| 3.4.22.36 | monosodium urate | - |
Homo sapiens | |
| 3.4.22.36 | poly(dA-dT) | - |
Homo sapiens |
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 3.4.22.36 | - |
Homo sapiens |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.22.36 | carbobenzoxy-valylalanyl-aspartyl-fluoromethylketone | - |
Homo sapiens | |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.22.36 | additional information | Homo sapiens | caspase-1-cleaved peptides show propensity for hydrophobic residues at P4 | ? | - |
? | |
| 3.4.22.36 | pro-interleukin-1beta + H2O | Homo sapiens | - |
mature interleukin-1beta + ? | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.22.36 | Homo sapiens | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.4.22.36 | - |
Homo sapiens |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.4.22.36 | THP-1 cell | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.22.36 | DNA replication licensing factor MCM4 + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.4.22.36 | eukaryotic translation initiation factor 3 subunit J + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.4.22.36 | gasdermin D + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.4.22.36 | additional information | caspase-1-cleaved peptides show propensity for hydrophobic residues at P4 | Homo sapiens | ? | - |
? | |
| 3.4.22.36 | pro-interleukin-1beta + H2O | - |
Homo sapiens | mature interleukin-1beta + ? | - |
? | |
| 3.4.22.36 | splicing factor U2AF 65-kDa subunit + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.4.22.36 | synapse-associated protein 1 + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.4.22.36 | zyxin + H2O | - |
Homo sapiens | ? | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.4.22.36 | cysteine aspartyl protease-1 | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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