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Literature summary extracted from

  • Paernaenen, P.; Meurman, J.H.; Samaranayake, L.; Virtanen, I.
    Human oral keratinocyte E-cadherin degradation by Candida albicans and Candida glabrata (2010), J. Oral Pathol. Med., 39, 275-278.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.23.24 pepstatin A
-
 Candida albicans
3.4.23.24 pepstatin A
-
 Nakaseomyces glabratus

Organism

EC Number Organism UniProt Comment Textmining
3.4.23.24 Candida albicans
-
 strains CCUG 32723, SC5314, HLC52, HLC54, JKC19, and B1134
-
3.4.23.24 Nakaseomyces glabratus
-
 strains ATCC 90030, 5WT, and G212
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.23.24 E-cadherin + H2O Candida albicans strains JKC19 and SC5314 degrade E-cadherin at pH 4.0, the 10fold concentrated growth media of the strains HLC-52, HLC-54, 32723 and B1134 cause degradation at pH 4.0, strains HLC-52 and HLC-54 also at pH 6.0 Candida albicans ?
-
 ?
3.4.23.24 additional information Candida glabrata does not degrade E-cadherin Nakaseomyces glabratus ?
-
 ?
3.4.23.24 additional information Candida albicans strain SC5314 Sap1-6 mutants do not degrade E-cadherin Candida albicans ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.23.24 SAP
-
 Nakaseomyces glabratus
3.4.23.24 SAP
-
 Candida albicans
3.4.23.24 secreted aspartic proteinase
-
 Nakaseomyces glabratus
3.4.23.24 secreted aspartic proteinase
-
 Candida albicans