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Literature summary extracted from

  • Al-Dabbagh, B.; Blanot, D.; Mengin-Lecreulx, D.; Bouhss, A.
    Preparative enzymatic synthesis of polyprenyl-pyrophosphoryl-N-acetylglucosamine, an essential lipid intermediate for the biosynthesis of various bacterial cell envelope polymers (2009), Anal. Biochem., 391, 163-165.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.8.33 membrane integral membrane protein Thermotoga maritima 16020
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Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.8.33 UDP-N-acetyl-D-glucosamine + ditrans,polycis-undecaprenyl phosphate Thermotoga maritima the product ditrans,polycis-undecaprenyl-N-acetyl-D-glucosaminyl diphosphate is an essential lipid intermediate for the biosynthesis of various bacterial cell envelope components UMP + N-acetyl-D-glucosaminyldiphospho-ditrans,polycis-undecaprenol
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 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.8.33 Thermotoga maritima Q9X1N5
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Purification (Commentary)

EC Number Purification (Comment) Organism
2.7.8.33
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 Thermotoga maritima

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.8.33 UDP-N-acetyl-D-glucosamine + ditrans,polycis-undecaprenyl phosphate the product ditrans,polycis-undecaprenyl-N-acetyl-D-glucosaminyl diphosphate is an essential lipid intermediate for the biosynthesis of various bacterial cell envelope components Thermotoga maritima UMP + N-acetyl-D-glucosaminyldiphospho-ditrans,polycis-undecaprenol
-
 ?
2.7.8.33 UDP-N-acetyl-D-glucosamine + ditrans,polycis-undecaprenyl phosphate the reverse reaction is about 1% of the forward reaction Thermotoga maritima UMP + N-acetyl-D-glucosaminyldiphospho-ditrans,polycis-undecaprenol
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 ?
2.7.8.33 UDP-N-acetyl-D-glucosamine + heptaprenyl phosphate
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 Thermotoga maritima UMP + N-acetyl-D-glucosaminyldiphospho-heptaprenol
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 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.8.33 WecA transferase
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 Thermotoga maritima

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.7.8.33 65
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 assay at Thermotoga maritima

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.7.8.33 8
-
 assay at Thermotoga maritima