Literature summary extracted from

Issigonis, M.; Tulina, N.; de Cuevas, M.; Brawley, C.; Sandler, L.; Matunis, E.
JAK-STAT signal inhibition regulates competition in the Drosophila testis stem cell niche (2009), Science, 326, 153-156.

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.7.10.2	Drosophila melanogaster	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
2.7.10.2	testis	-	Drosophila melanogaster	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.7.10.2	ATP + signal transducer and activator of transcription	-	Drosophila melanogaster	ADP + phospho-L-tyrosinyl-signal transducer and activator of transcription	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
2.7.10.2	JAK	-	Drosophila melanogaster
2.7.10.2	Janus kinase	-	Drosophila melanogaster

Cofactor

EC Number	Cofactor	Comment	Organism	Structure
2.7.10.2	ATP	-	Drosophila melanogaster

General Information

EC Number	General Information	Comment	Organism
2.7.10.2	physiological function	JAK-STAT signaling is required for germline stem cell and cyst progenitor cells maintenance in testis	Drosophila melanogaster

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Release 2023.1 (January 2023)