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Literature summary extracted from

  • Ober, D.; Kaltenegger, E.
    Pyrrolizidine alkaloid biosynthesis, evolution of a pathway in plant secondary metabolism (2009), Phytochemistry, 70, 1687-1695.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.5.1.45 expressed in Escherichia coli Senecio vernalis
2.5.1.45 expressed in Escherichia coli Phalaenopsis sp.

Organism

EC Number Organism UniProt Comment Textmining
2.5.1.45 Phalaenopsis sp.
-
-
-
2.5.1.45 Senecio vernalis
-
-
-
2.5.1.46 Leishmania donovani
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.5.1.45 flower HSS expression stops just before the flower buds open Phalaenopsis sp.
-
2.5.1.45 root
-
Senecio vernalis
-
2.5.1.45 root
-
Phalaenopsis sp.
-
2.5.1.45 root in the roots of Eupatorium cannabinum, all cells of the cortex parenchyma are found to express HSS, but not the cells of the endodermis Senecio vernalis
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.5.1.45 putrescine + spermidine
-
Senecio vernalis N-(4-aminobutyl)butane-1,4-diamine + propane-1,3-diamine
-
?
2.5.1.45 putrescine + spermidine
-
Phalaenopsis sp. N-(4-aminobutyl)butane-1,4-diamine + propane-1,3-diamine
-
?

Synonyms

EC Number Synonyms Comment Organism
2.5.1.45 HSS
-
Senecio vernalis
2.5.1.45 HSS
-
Phalaenopsis sp.
2.5.1.46 deoxyhypusine synthase
-
Leishmania donovani

Cofactor

EC Number Cofactor Comment Organism Structure
2.5.1.45 NAD+
-
Senecio vernalis
2.5.1.45 NAD+
-
Phalaenopsis sp.