Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Jackson, S.K.; Abate, W.; Tonks, A.J.
    Lysophospholipid acyltransferases: novel potential regulators of the inflammatory response and target for new drug discovery (2008), Pharmacol. Ther., 119, 104-114.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.23 2-[5-(thiophen-3-yl)pyridin-3-yl]ethanol non-competitive Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.1.23 0.027
-
 lysophosphatidylcholine
-
 Bos taurus
2.3.1.23 0.1
-
 oleoyl-CoA
-
 Bos taurus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.23 microsome
-
 Rattus norvegicus
-
-
2.3.1.23 microsome
-
 Bos taurus
-
-
2.3.1.23 microsome
-
 Mus musculus
-
-

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.23 Bos taurus
-
-
-
2.3.1.23 Homo sapiens Q8NF37
-
-
2.3.1.23 Mus musculus Q3TFD2
-
-
2.3.1.23 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.23 liver
-
 Rattus norvegicus
-
2.3.1.23 lung
-
 Rattus norvegicus
-
2.3.1.23 lung
-
 Mus musculus
-
2.3.1.23 monocyte
-
 Homo sapiens
-
2.3.1.23 neutrophil
-
 Homo sapiens
-
2.3.1.23 retina outer rod segment Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.23 lysophosphatidylcholine + acyl-CoA
-
 Rattus norvegicus phosphatidylcholine + CoA
-
 ?
2.3.1.23 lysophosphatidylcholine + acyl-CoA
-
 Mus musculus phosphatidylcholine + CoA
-
 ?
2.3.1.23 lysophosphatidylcholine + acyl-CoA
-
 Homo sapiens phosphatidylcholine + CoA
-
 ?
2.3.1.23 lysophosphatidylcholine + oleoyl-CoA
-
 Bos taurus phosphatidylcholine + CoA
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.3.1.23 1-acylglycerophosphocholine acyltransferase
-
 Rattus norvegicus
2.3.1.23 1-acylglycerophosphocholine acyltransferase
-
 Bos taurus
2.3.1.23 1-acylglycerophosphocholine acyltransferase
-
 Mus musculus
2.3.1.23 1-acylglycerophosphocholine acyltransferase
-
 Homo sapiens
2.3.1.23 LPCAT
-
 Rattus norvegicus
2.3.1.23 LPCAT
-
 Bos taurus
2.3.1.23 LPCAT
-
 Mus musculus
2.3.1.23 LPCAT
-
 Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.3.1.23 7
-
-
 Bos taurus