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Literature summary extracted from

  • Sales, I.M.; Freitas, R.L.; Saldanha, G.B.; Souza, G.F.; Freitas, R.M.
    Choline acetyltransferase and acetylcholinesterase activities are reduced in rat striatum and frontal cortex after pilocarpine-induced seizures (2010), Neurosci. Lett., 469, 81-83.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.6 bromoacetylcholine a selective inhibitor of choline acetyltransferase Rattus norvegicus
2.3.1.6 pilocarpine the enzyme activity in striatum and frontal cortex is reduced after pilocarpine-induced seizures Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.6 acetyl-CoA + choline Rattus norvegicus
-
 CoA + O-acetylcholine
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.6 Rattus norvegicus
-
 male Wistar rats
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.6 brain
-
 Rattus norvegicus
-
2.3.1.6 frontal cortex
-
 Rattus norvegicus
-
2.3.1.6 striatum
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.6 acetyl-CoA + choline
-
 Rattus norvegicus CoA + O-acetylcholine
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.3.1.6 ChAT
-
 Rattus norvegicus
2.3.1.6 choline acetyltransferase
-
 Rattus norvegicus